A cross-sectional survey of urinary iodine status in Latvia
Materials and methods: We conducted a cross-sectional school-based cluster survey of 915 children aged 9–12 years in 46 randomly selected schools in all regions of Latvia. Urine samples, questionnaires on the consumption of iodized salt and information on socioeconomic status were collected. TSH levels in newborns were also measured.
Results: The median creatinine-standardized urinary iodine concentration (UIC) in our study was 107.3 mg/g Cr. UIC measurements indicative of mild iodine deficiency were present in 31.6%, moderate deficiency in 11.9% and severe deficiency in 2.8% of the participants. The prevalence of iodine deficiency was the highest in the southeastern region of Latgale and the northeastern region of Vidzeme. The prevalence of TSH values >5 mIU/L followed a similar pattern. The self-reported prevalence of regular iodized salt consumption was 10.2%. Children from urban schools had a significantly lower UIC than children from rural schools.
Conclusions: Our findings suggest that although the overall median UIC in Latvian schoolchildren falls within the lower normal range, almost 50% of the schoolchildren are iodine deficient, especially in urban schools and in the eastern part of Latvia. The absence of a mandatory salt iodization program puts a significant number of children and pregnant women at risk.
Konrade, I.; Neimane, L.; Makrecka, M.; Strele, I.; Liepinsh, E.; Lejnieks, A.; Vevere, P.; Gruntmanis, U.; Pīrāgs, V.; Dambrova, M. A cross-sectional survey of urinary iodine status in Latvia. Medicina 2014, 50, 124-129.
Konrade I, Neimane L, Makrecka M, Strele I, Liepinsh E, Lejnieks A, Vevere P, Gruntmanis U, Pīrāgs V, Dambrova M. A cross-sectional survey of urinary iodine status in Latvia. Medicina. 2014; 50(2):124-129.Chicago/Turabian Style
Konrade, Ilze; Neimane, Lolita; Makrecka, Marina; Strele, Ieva; Liepinsh, Edgars; Lejnieks, Aivars; Vevere, Parsla; Gruntmanis, Ugis; Pīrāgs, Valdis; Dambrova, Maija. 2014. "A cross-sectional survey of urinary iodine status in Latvia." Medicina 50, no. 2: 124-129.