Treatment of Tuberculosis in South Kazakhstan: Clinical and Economical Aspects
Material and Methods. In total, 502 patients participated in the study. They were hospitalized to the tuberculosis dispensary of Sayram district (South Kazakhstan province) in 2007–2013. Statistical analysis included logistic regression for better treatment outcomes and analysis of antibiotic treatment costs.
Results. Two-thirds of patients had infiltrative tuberculosis (67%). Positive treatment outcomes were determined in 85% of cases. The patients were mostly treated with cycloserine, protionamide, capreomycin, and ofloxacin. The majority of antibiotic costs were related to the treatment with capreomycin. In case of the positive results of the test for Mycobacterium tuberculosis, antibiotic expenses were almost 3 times greater than in case of negative test results (P<0.001).
Conclusions. The majority of patients had extensively drug-resistant tuberculosis. The negative results of the test for Mycobacterium tuberculosis at discharge were not related to pretreatment factors. Antibiotic-related costs were significantly higher in case of the positive results of the test of Mycobacterium tuberculosis, but were not associated with gender, residence place, hospitalization recurrence, or main blood test results before treatment.
Maimakov, T.; Sadykova, L.; Kalmataeva, Z.; Kurakpaev, K.; Šmigelskas, K. Treatment of Tuberculosis in South Kazakhstan: Clinical and Economical Aspects. Medicina 2013, 49, 52.
Maimakov T, Sadykova L, Kalmataeva Z, Kurakpaev K, Šmigelskas K. Treatment of Tuberculosis in South Kazakhstan: Clinical and Economical Aspects. Medicina. 2013; 49(7):52.Chicago/Turabian Style
Maimakov, Talgat; Sadykova, Laura; Kalmataeva, Zhanna; Kurakpaev, Kural; Šmigelskas, Kastytis. 2013. "Treatment of Tuberculosis in South Kazakhstan: Clinical and Economical Aspects." Medicina 49, no. 7: 52.