Cognitive Profile and Depressive Symptoms in Patients With Epilepsy
Material and Methods. A total of 36 patients with focal epilepsy and 26 patients with generalized epilepsy were compared with the control group of healthy volunteers (n=53). A battery of neuropsychological tests assessing verbal and visual spatial memory and executive functioning was carried out in addition to the completion of the Beck Depression Inventory (BDI).
Results. The results indicated that patients with epilepsy performed significantly worse than controls on all verbal memory subscales and verbal fluency domains. The patients with focal epilepsy scored significantly worse than the patients with generalized epilepsy. The BDI scores were significantly correlated with several scores of the cognitive test in both patients’ groups but not in the control group.
Conclusions. Our results suggest that patients with epilepsy, especially with focal-onset epilepsy, show cognitive disturbances predominantly in the verbal memory domain. In addition, depression was found to have a negative effect on cognitive functioning in patients with epilepsy.
Liik, M.; Vahter, L.; Gross-Paju, K.; Haldre, S. Cognitive Profile and Depressive Symptoms in Patients With Epilepsy. Medicina 2013, 49, 41.
Liik M, Vahter L, Gross-Paju K, Haldre S. Cognitive Profile and Depressive Symptoms in Patients With Epilepsy. Medicina. 2013; 49(6):41.Chicago/Turabian Style
Liik, Maarika; Vahter, Liina; Gross-Paju, Katrin; Haldre, Sulev. 2013. "Cognitive Profile and Depressive Symptoms in Patients With Epilepsy." Medicina 49, no. 6: 41.