Ultrasonography and Magnetic Resonance Imaging of the Brain in Hypoxic Full-Term Newborns
Materials and Methods. A systematic search of studies on the diagnostic and prognostic possibilities of radiological investigations for the detection of hypoxic-ischemic injuries in full-term newborns was performed.
Results. A total of 13 prospective and 4 retrospective studies that analyzed the incidence of hypoxic-ischemic cerebral injuries, determined by means of cranial sonography, Doppler sonography, and magnetic resonance imaging, and associations with the stages of hypoxic-ischemic encephalopathy and long-term neurodevelopmental outcomes were included in this systematic review.
Conclusions. Magnetic resonance imaging detects lesions in 75%–100% of cases. Magnetic resonance imaging performed at the age of 7–11 days demonstrated a high sensitivity (100%) and negative predictive value (100%) to predict unfavorable outcomes at 4 years of age. In newborns with hypoxic-ischemic encephalopathy, substantial cerebral hemodynamic alterations are detected after birth. The sensitivity and negative predictive value of cerebral blood flow velocities (peak systolic flow velocity, end-diastolic flow velocity) changes at 12±2 hours of age to predict the severity of hypoxic-ischemic encephalopathy and unfavorable outcomes at 18 months of age were found to be high (90% and 94%, respectively). A low resistive index (<0.56) at the age of 1–3 days had a specificity of 95% to predict unfavorable outcomes at 3 years of age. The data on the diagnostic and prognostic potential of cranial sonography are limited scarce and contrary.
Kudrevičienė, A.; Lukoševičius, S.; Laurynaitienė, J.; Marmienė, V.; Tamelienė, R.; Basevičius, A. Ultrasonography and Magnetic Resonance Imaging of the Brain in Hypoxic Full-Term Newborns. Medicina 2013, 49, 8.
Kudrevičienė A, Lukoševičius S, Laurynaitienė J, Marmienė V, Tamelienė R, Basevičius A. Ultrasonography and Magnetic Resonance Imaging of the Brain in Hypoxic Full-Term Newborns. Medicina. 2013; 49(1):8.Chicago/Turabian Style
Kudrevičienė, Aušrelė; Lukoševičius, Saulius; Laurynaitienė, Jūratė; Marmienė, Vitalija; Tamelienė, Rasa; Basevičius, Algidas. 2013. "Ultrasonography and Magnetic Resonance Imaging of the Brain in Hypoxic Full-Term Newborns." Medicina 49, no. 1: 8.