Postoperative Survival in Patients With Multiple Brain Metastases
Material and Methods. The records of the patients who underwent surgical resection of 2 or more lesions between January 2005 and January 2010 were retrospectively reviewed. Survival was calculated from the date of surgery to the last follow-up evaluation or death, and different clinical factors were analyzed in regard to patient survival.
Results. In total, 36 patients underwent one or more craniotomies. The survival of the total group ranged from 16 days to 37.5 months (mean, 29 months). There were 4 deaths within 30 days. When divided into Radiation Therapy Oncology Group RPA classes, the survival time was 11.75, 8.58, and 5.31 months for classes 1, 2, and 3, respectively. Regarding an impact on the survival, a significant association with a favorable outcome was found for the following factors: the number of brain metastases (2–3 vs. 4–6, P=0.046), RPA classes (1 vs. 2 or 3, P=0.0192), and extent of metastasis resection (all vs. partial, P=0.018).
Conclusions. Well-selected patients with multiple brain metastases appear to benefit from surgery compared with historical controls of patients treated with whole-brain radiotherapy alone.
Auslands, K.; Apškalne, D.; Bicāns, K.; Ozols, R.; Ozoli, H. Postoperative Survival in Patients With Multiple Brain Metastases. Medicina 2012, 48, 41.
Auslands K, Apškalne D, Bicāns K, Ozols R, Ozoli H. Postoperative Survival in Patients With Multiple Brain Metastases. Medicina. 2012; 48(6):41.Chicago/Turabian Style
Auslands, Kaspars; Apškalne, Daina; Bicāns, Kārlis; Ozols, Rolfs; Ozoli, Henrijs. 2012. "Postoperative Survival in Patients With Multiple Brain Metastases." Medicina 48, no. 6: 41.