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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
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Two Dog-Related Infections Leading to Death: Overwhelming Capnocytophaga canimorsus Sepsis in a Patient With Cystic Echinococcosis

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Department of Infectious, Chest Diseases, Dermatovenerology and Allergology, Vilnius University
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Centre of Anesthesiology, Intensive Therapy and Pain Treatment, Vilnius University Hospital Santariškių Klinikos, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2012, 48(2), 11; https://doi.org/10.3390/medicina48020011
Received: 28 May 2010 / Accepted: 28 February 2012 / Published: 4 March 2012
Capnocytophaga canimorsus is a fastidious, capnophilic, fusiform, and filamentous gram-negative rod. It is part of the normal oral flora of dogs and cats and can cause an infection in humans, but is of generally low virulence in healthy individuals. A case of fatal sepsis due to Capnocytophaga canimorsus in a 46-year-old woman with clinically silent cystic echinococcosis discovered postmortem is present. She had been bitten by a dog 3 days before the symptoms appeared. The family had owned the dog for 4 years. A preliminary diagnosis of septic shock of unknown etiology with multisystem organ failure was established. Despite all the efforts, the patient died on the seventh day of hospitalization. Laboratory findings received postmortem showed Capnocytophaga canimorsus isolated from the blood culture after 7 incubation days. Autopsy showed a cyst in the liver with a fibrotic wall and necrotic eosinophilic interiors containing fragments of Echinococcus granulosus scolices. In conclusion, an interaction possibly established long ago between the host and Echinococcus granulosus conditioned immunosuppression mechanisms developed by the parasite in this case, which can explain such an aggressive course of the infection with Capnocytophaga. Two dog-related infections were fatal in the middle-aged dog owner considered healthy before this hospitalization. Vigilance concerning recent exposure to dogs or cats and potential immunosuppression risk factors must be maintained in a patient presenting with clinical features of fulminant sepsis.
Keywords: Capnocytophaga canimorsus; Echinococcus granulosus; fulminant sepsis; dogrelated infection Capnocytophaga canimorsus; Echinococcus granulosus; fulminant sepsis; dogrelated infection
MDPI and ACS Style

Matulionytė, R.; Lisauskienė, I.; Kėkštas, G.; Ambrozaitis, A. Two Dog-Related Infections Leading to Death: Overwhelming Capnocytophaga canimorsus Sepsis in a Patient With Cystic Echinococcosis. Medicina 2012, 48, 11.

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