Tear Nitric Oxide Levels in Behçet’s Disease
Results. The tear nitrate/nitrite levels were 0.06 nmol/μL (SD, 0.05) in the active disease group, 0.05 nmol/μL (SD, 0.05) in the inactive disease group, and 0.02 nmol/μL (SD, 0.01) in the control group. The tear nitrate/nitrite levels of both active and inactive groups were higher than those of the control group (P=0.001 and P=0.047, respectively), but there was no significant difference between the active and inactive groups.
Conclusion. Our results demonstrated that the tear NO levels were elevated in the patients with Behçet’s disease. We imply that a better understanding of NO function in the pathogenesis of Behçet uveitis is necessary to develop new therapies based on the inhibitors of NO synthases.
İşcan, Y.; Yiğit, U.; Tuğcu Çakmak, B.; Erdoğan, M.; Erdoğan, D.A.; Öner, V.; Taş, M.; Özyazgan, Y. Tear Nitric Oxide Levels in Behçet’s Disease. Medicina 2012, 48, 81.
İşcan Y, Yiğit U, Tuğcu Çakmak B, Erdoğan M, Erdoğan DA, Öner V, Taş M, Özyazgan Y. Tear Nitric Oxide Levels in Behçet’s Disease. Medicina. 2012; 48(11):81.Chicago/Turabian Style
İşcan, Yalçın; Yiğit, Ulviye; Tuğcu Çakmak, Betül; Erdoğan, Mehmet; Erdoğan, Derya A.; Öner, Veysi; Taş, Mehmet; Özyazgan, Yılmaz. 2012. "Tear Nitric Oxide Levels in Behçet’s Disease." Medicina 48, no. 11: 81.