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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Total Antioxidant Capacity of Venous Blood, Blood Plasma, and Serum of Patients With Periodontitis, and the Effect of Traumeel S on These Characteristics

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Public Institution “Odontologijos studija”
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Department of Maxillofacial Surgery, Medical Academy, Lithuanian University of Health Sciences
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Department of Dental and Maxillofacial Orthopedics, Medical Academy, University of Health Sciences, Lithuania
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Author to whom correspondence should be addressed.
Medicina 2011, 47(4), 27; https://doi.org/10.3390/medicina47040027
Received: 23 February 2011 / Accepted: 15 April 2011 / Published: 20 April 2011
Introduction. Periodontal diseases are among the most common chronic infections in humans. Chronic low-level bacteremia and a septicemic inflammatory response have been suggested as a pathogenetic link between periodontal disease and atherosclerosis, diabetes and other systemic diseases. All this significantly increases the relevance of the search for the means for treatment and prevention of periodontal diseases. The aim of the present study was to evaluate blood count and the antioxidant capacity of venous blood, blood plasma, and serum in patients with periodontitis and control subjects with healthy periodontal tissues, and to investigate the effect of the homeopathic medication Traumeel S on the antioxidant capacity of venous blood, plasma, and serum.
Material and Methods.
The study was performed using venous blood of 21 individuals with chronic periodontitis and 22 healthy subjects. Reduction properties of venous blood, blood plasma, and serum were investigated using the method of reduction of nitroblue tetrazolium, proposed by Demehin et al.
Results. The data showed that there was no significant difference in venous blood hemoglobin levels or erythrocyte counts between the groups, while significantly higher leukocyte counts were observed in the periodontitis group (P<0.05). The antioxidant capacity of blood plasma was significantly higher in the periodontitis group than it was in the controls (P<0.05). Meanwhile, the antioxidant capacity of serum was significantly lower in the periodontitis group as compared with controls (P<0.05). The preparation Traumeel S had no effect on the antioxidant capacity of venous blood or blood plasma in the studied groups.
Conclusions. Compared to healthy individuals, the antioxidant capacity of blood plasma in patients with periodontitis was higher, while the antioxidant capacity of serum was lower. The homeopathic medication Traumeel S had no effect on the antioxidant capacity of venous blood, blood plasma, or serum. Our findings concerning the elevated leukocyte counts in venous blood of patients with periodontitis confirm the presumption that periodontal diseases cause low-grade systemic inflammation induced by the host response to periodontal bacteria.
Keywords: blood count; antioxidant capacity; nitroblue tetrazolium; periodontitis; Traumeel S blood count; antioxidant capacity; nitroblue tetrazolium; periodontitis; Traumeel S
MDPI and ACS Style

Žilinskas, J.; Kubilius, R.; Žekonis, G.; Žekonis, J. Total Antioxidant Capacity of Venous Blood, Blood Plasma, and Serum of Patients With Periodontitis, and the Effect of Traumeel S on These Characteristics. Medicina 2011, 47, 27.

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