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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Ultrasonic measurement of ocular rectus muscle thickness in patients with Graves’ ophthalmopathy

Institute for Biomedical Research, Kaunas University of Medicine
Lithuanian Academy of Physical Education
Department of Ophthalmology, Kaunas University of Medicine, Lithuania
Author to whom correspondence should be addressed.
Medicina 2010, 46(7), 472;
Received: 22 May 2009 / Accepted: 8 July 2010 / Published: 13 July 2010
The aim of this study was to evaluate changes in extraocular muscle thickness and to assess its correlation with the degree of proptosis in patients with Graves’ ophthalmopathy (GO).
Material and methods. A total of 242 patients (207 females and 35 males) with Graves’ ophthalmopathy were enrolled into the study (GO group). Their mean age was 53.83±14.49 years. In addition, we examined an age-matched (53.51±12.79 years) control group of 40 healthy persons. All the participants underwent ophthalmological examination, including eye protrusion measurement and ultrasonographic evaluation of extraocular muscles thickness.
. The mean exophthalmos in the GO and control groups was 17.84±2.79 mm and 16.0±1.58 mm, respectively. The enlargement of inferior rectus muscle was recorded in 92.1% of patients, lateral rectus muscle in 81.2%, and medial rectus muscle in 50.8% (P<0.001). A significant correlation between exophthalmos and muscle thickness sum was found in the GO group (Spearman correlation coefficient, 0.515; P<0.0001).
. Graves’ ophthalmopathy is more frequent in medium-aged women than men. A significant enlargement of inferior, lateral, and medial straight muscles was noticed in the GO group. With increasing proptosis, the sum of the muscle thickness was increasing, and exophthalmos moderately correlated with muscle thickness sum.
Keywords: Graves’ ophthalmopathy; extraocular muscle; proptosis; ultrasonography Graves’ ophthalmopathy; extraocular muscle; proptosis; ultrasonography
MDPI and ACS Style

Imbrasienė, D.; Jankauskienė, J.; Stanislovaitienė, D. Ultrasonic measurement of ocular rectus muscle thickness in patients with Graves’ ophthalmopathy. Medicina 2010, 46, 472.

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