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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Gliomatosis cerebri

Department of Radiology, Kaunas University of Medicine
Department of Neurology, Kaunas University of Medicine
Vilnius Oncology Hospital, Lithuania
Author to whom correspondence should be addressed.
Medicina 2010, 46(5), 341;
Received: 16 April 2009 / Accepted: 7 May 2010 / Published: 12 May 2010
Gliomatosis cerebri is a rare diffusely infiltrating glial tumor involving two or more lobes and is frequently is bilateral. Infiltrative extent of tumor is out of proportion to histological and clinical features. We present a case in which finally the diagnosis of gliomatosis cerebri was made. In this case, computed tomography showed that midline structures were insignificantly shifted to the left, there was a mild dilatation of lateral ventricles more expressed on the right, and no pathologic changes of brain tissue density were found. On magnetic resonance tomography, T2W/SE and T2W/FLAIR images revealed zones of hyperintense signal, spreading with time, through several lobes of the brain with no enhancement on T1W images. Diagnosis of gliomatosis cerebri was suspected, stereotaxic biopsy was performed, and pathological examination revealed changes typical of diffuse glial tumor. In this article, changes typical of gliomatosis cerebri seen in other radiological methods such as computed tomography, magnetic resonance spectroscopy, dynamic contrast-enhanced T2*-weighted magnetic resonance, and positron emission tomography also are discussed.
Keywords: gliomatosis cerebri; magnetic resonance tomography; stereotaxic biopsy gliomatosis cerebri; magnetic resonance tomography; stereotaxic biopsy
MDPI and ACS Style

Gleiznienė, R.; Bučinskas, U.; Lukoševičius, S.; Vaitkus, A.; Letautienė, S.; Apanavičiūtė, D.; Galvonaitė, M. Gliomatosis cerebri. Medicina 2010, 46, 341.

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