Next Article in Journal
Comparative diagnostic value of contrast-enhanced ultrasonography, computed tomography, and magnetic resonance imaging in diagnosis of hepatic hemangiomas
Previous Article in Journal
The effect of induced sputum and bronchoalveolar lavage fluid from patients with chronic obstructive pulmonary disease on neutrophil migration in vitro
Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Surgical treatment of metastatic tumors of the femur

1
Department of Orthopedics and Traumatology, Kaunas University of Medicine
2
Department of Surgery, Kaunas University of Medicine, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2010, 46(5), 323; https://doi.org/10.3390/medicina46050045
Received: 30 January 2009 / Accepted: 7 May 2010 / Published: 12 May 2010
Objective. To evaluate the patients functional outcome and pain control after resection of metastatic femoral tumors.
Material and methods
. A prospective randomized clinical study was conducted, which included 26 cases of metastatic tumors of the femur with an associated pathologic fracture. These selected cases were randomly divided into two groups based upon the using of methylmethacrylate cement in fracture fixation. Group 1 (n=13) included all cases where the fractures were treated with bone cement augmentation. Group 2 (n=13) included all cases where the fractures were treated without bone cement augmentation. Functional outcome was evaluated according the American Musculoskeletal Tumor Society system.
Results
. Good and excellent pain control was achieved in 61.5%, satisfactory in 38.5% of all cases in the Group 1 versus 15.5% (P=0.015) and 69% (χ2=2.4762; P=0.115) of all cases in the Group 2. Functional outcome after femoral metastasis resection and pathologic fracture fixation was significantly better in the Group 1. Total lower extremity function of full normal function was 67% in the Group 1 versus 49% in the Group 2 (P<0.05). We did not observe significant difference between patients’ postoperative survival in the groups (P>0.05). The postoperative durability of stable pathologic fracture fixation was shorter in the Group 2 (273.9±51.7 vs. 358.9±116.8 days) comparing with Group 1 (P=0.03).
Conclusions. The introduction of bone cement as the adjunct to the pathologic femoral fracture fixation significantly improved the clinical our study results: we achieved better functional outcome and better pain control.
Keywords: metastatic bone tumors; pathologic fractures fixation; bone cement; methylmethacrylate metastatic bone tumors; pathologic fractures fixation; bone cement; methylmethacrylate
MDPI and ACS Style

Toliušis, V.; Kalesinskas, R.J.; Kiudelis, M.; Maleckas, A.; Grikšas, M. Surgical treatment of metastatic tumors of the femur. Medicina 2010, 46, 323.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop