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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Factors influencing development of atrial fibrillation after implantation of cardiac pacemaker for sinus node dysfunction

1
Clinic of Heart Diseases, Vilnius University
2
Center of Cardiology and Angiology, Clinics of Santariškės, Vilnius University Hospital, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2009, 45(3), 169; https://doi.org/10.3390/medicina45030022
Received: 11 February 2008 / Accepted: 5 February 2009 / Published: 10 February 2009
Objective. The aim of this study was to evaluate factors influencing the success of atrial fibrillation treatment associated with the sick sinus syndrome after pacemaker implantation.
Methods and results
. In 163 patients with sick sinus syndrome followed up after pacemaker implantation, statistical analysis showed that the recurrence of atrial fibrillation increased 2.8 times and 2.5 times when the left atrium or the right atrium, respectively, were increased by 1 cm (P=0.001). In addition, the recurrence of atrial fibrillation increased 2.5 times when the interventricular septum was thickened (P=0.007). Probability of atrial fibrillation recurrence was 2.73 times higher in the presence of grade II mitral regurgitation as compared to absent or grade I mitral regurgitation (P=0.029). The results of atrial fibrillation treatment did not significantly depend on age, gender, duration of atrial fibrillation symptoms, other cardiac structural changes, and concomitant noncardiac diseases.
Conclusions. In patients with sick sinus syndrome, the effectiveness of atrial fibrillation treatment after pacemaker implantation is influenced by enlargement of the left and the right atria, increased interventricular septum thickness, and grade II mitral regurgitation. Evaluation of echocardiographic data before pacemaker implantation has prognostic value for determining the probability of maintenance of sinus rhythm.
Keywords: cardiac pacing; atrial fibrillation; sick sinus syndrome; echocardiography cardiac pacing; atrial fibrillation; sick sinus syndrome; echocardiography
MDPI and ACS Style

Aidietis, A.; Barysienė, J.; Marinskis, G.; Aidietienė, S.; Kairevičiūtė, D.; Jurkuvėnas, P.; Aganauskienė, J.; Bagdonas, K.; Ježovas, V.; Laucevičius, A. Factors influencing development of atrial fibrillation after implantation of cardiac pacemaker for sinus node dysfunction. Medicina 2009, 45, 169.

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