Usefulness of assessment of voice capabilities in female patients with reflux-related dysphonia
Material and methods. Six parameters of voice range profile (VRP) and five parameters of speech range profile were taken and analyzed from 60 dysphonic outpatient females with laryngopharyngeal reflux (LPR) diagnosed by reflux-related atypical and typical symptoms, videolaryngoscopic findings, upper gastrointestinal endoscopy, and positive response to empiric 3-month omeprazole treatment. Seventy-six females with healthy voice served as controls.
Results. All six parameters of voice range profile and three of 5 parameters of speech range profile showed significant differences comparing LPR patients with controls before omeprazole treatment (P<0.05). Logistic regression analysis revealed VRP maximum-minimum intensity range to be the most informative parameter for discrimination between reflux-related dysphonic and healthy voices (overall prediction accuracy, 86.8%). A threshold value of significant parameter was stated using the receiver operating characteristic curve. Treatment with omeprazole significantly improved voice quality showing the greatest changes in the mean scores of majority of voice range profile parameters.
Conclusions. Vocal capabilities, especially evaluated by voice range profile, are restricted in LPR female patients in comparison to subjects with healthy voice. Quantitative voice assessment with voice range profile may add more objective aspect for screening dysphonia and could be used as a criterion of evaluation of treatment efficacy in such patients.
Šiupšinskienė, N.; Adamonis, K.; Toohill, R.J. Usefulness of assessment of voice capabilities in female patients with reflux-related dysphonia. Medicina 2009, 45, 978.
Šiupšinskienė N, Adamonis K, Toohill RJ. Usefulness of assessment of voice capabilities in female patients with reflux-related dysphonia. Medicina. 2009; 45(12):978.Chicago/Turabian Style
Šiupšinskienė, Nora; Adamonis, Kęstutis; Toohill, Robert J. 2009. "Usefulness of assessment of voice capabilities in female patients with reflux-related dysphonia." Medicina 45, no. 12: 978.