Next Article in Journal
A prospective comparison of double- and single-bundle anterior cruciate ligament reconstructions
Previous Article in Journal
Soluble interleukin-2 receptor and tumor necrosis factor levels in depressed patients in Estonia
Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Usefulness of assessment of voice capabilities in female patients with reflux-related dysphonia

1
Department of Otorhinolaryngology
2
Department of Gastroenterology, Kaunas University of Medicine, Lithuania
3
Department of Otolaryngology and Communications Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
*
Author to whom correspondence should be addressed.
Medicina 2009, 45(12), 978; https://doi.org/10.3390/medicina45120125
Received: 29 June 2009 / Accepted: 7 December 2009 / Published: 12 December 2009
Objectives. To analyze vocal capabilities in patients diagnosed with reflux related dysphonia versus controls with healthy voice with selection of the most informative discriminating quantitative parameters and to assess voice changes following treatment.
Material and methods
. Six parameters of voice range profile (VRP) and five parameters of speech range profile were taken and analyzed from 60 dysphonic outpatient females with laryngopharyngeal reflux (LPR) diagnosed by reflux-related atypical and typical symptoms, videolaryngoscopic findings, upper gastrointestinal endoscopy, and positive response to empiric 3-month omeprazole treatment. Seventy-six females with healthy voice served as controls.
Results
. All six parameters of voice range profile and three of 5 parameters of speech range profile showed significant differences comparing LPR patients with controls before omeprazole treatment (P<0.05). Logistic regression analysis revealed VRP maximum-minimum intensity range to be the most informative parameter for discrimination between reflux-related dysphonic and healthy voices (overall prediction accuracy, 86.8%). A threshold value of significant parameter was stated using the receiver operating characteristic curve. Treatment with omeprazole significantly improved voice quality showing the greatest changes in the mean scores of majority of voice range profile parameters.
Conclusions. Vocal capabilities, especially evaluated by voice range profile, are restricted in LPR female patients in comparison to subjects with healthy voice. Quantitative voice assessment with voice range profile may add more objective aspect for screening dysphonia and could be used as a criterion of evaluation of treatment efficacy in such patients.
Keywords: laryngopharyngeal reflux; quantitative voice assessment; voice range profile; speech range profile laryngopharyngeal reflux; quantitative voice assessment; voice range profile; speech range profile
MDPI and ACS Style

Šiupšinskienė, N.; Adamonis, K.; Toohill, R.J. Usefulness of assessment of voice capabilities in female patients with reflux-related dysphonia. Medicina 2009, 45, 978.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop