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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Epidural and general anesthesia versus general anesthesia in radical prostatectomy

Institute of Oncology, Vilnius University, Lithuania
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Medicina 2009, 45(10), 772; https://doi.org/10.3390/medicina45100100
Received: 10 November 2008 / Accepted: 6 September 2009 / Published: 11 September 2009
Induced hypotension with epidural anesthesia influences the intraoperative blood loss in prostate cancer patients undergoing radical prostatectomy. The aim of this study was to evaluate intraoperative blood loss and need of blood transfusions in patients who underwent radical prostatectomy under epidural/general anesthesia and general anesthesia. Two groups were selected: epidural/general anesthesia group (study group, 27 patients) received epidural anesthesia in association with general anesthesia, and general anesthesia group (control group, 27 patients) received general anesthesia alone. Epidural/general anesthesia was performed using 0.5% solution of bupivacaine and maintained by volatile anesthetic sevoflurane. General anesthesia was performed with endotracheal ventilation using sevoflurane and intravenous fentanyl. The present study showed that the mean blood loss in epidural/general anesthesia group was significantly lower in comparison with that of general anesthesia group (740±210 mL versus 1150±290 mL, P<0.001). In addition, less allogeneic blood was transfused in epidural/general anesthesia group: 0.19 blood units transfused versus 0.52 blood units in general anesthesia group (P=0.007). Our study proved that induced hypotension with epidural/general anesthesia reduced intraoperative blood loss and need of allogeneic blood transfusions in cancer patient undergoing open radical prostatectomy.
Keywords: epidural anesthesia; general anesthesia; radical prostatectomy; intraoperative blood loss epidural anesthesia; general anesthesia; radical prostatectomy; intraoperative blood loss
MDPI and ACS Style

Tikuišis, R.; Miliauskas, P.; Samalavičius, N.E.; Žurauskas, A.; Sruogis, A. Epidural and general anesthesia versus general anesthesia in radical prostatectomy. Medicina 2009, 45, 772.

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