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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Presurgical evaluation of epilepsy patients

1
Department of Neurology, Kaunas University of Medicine, Lithuania
2
Faculty of Medicine, Geneva University, and Presurgical Epilepsy Unit and Neurology Department, University Hospital of Geneva, Switzerland
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Author to whom correspondence should be addressed.
Medicina 2008, 44(8), 585; https://doi.org/10.3390/medicina44080076
Received: 18 January 2008 / Accepted: 6 August 2008 / Published: 11 August 2008
Epilepsy surgery has been established as an effective treatment in pharmacoresistant focal epilepsies. Most candidates for epilepsy surgery are patients with partial epilepsy syndromes refractory to medical treatment. The curative surgery procedure is resection of the epileptogenic zone; therefore, precise detection of the site responsible for seizure generation is necessary. Modern structural and functional imaging techniques have made presurgical evaluation less invasive and available for a higher number of patients. Video electroencephalography (EEG) monitoring, high-resolution structural and functional imaging techniques are used widely for presurgical evaluation. When noninvasive evaluation is not sufficient for the detection of the epileptogenic zone, invasive EEG monitoring and intracarotid amobarbital test are used. A classical example of a surgically curable epilepsy syndrome is mesial temporal lobe epilepsy with about 70–80% of patients becoming free of seizures after surgery. Results in extratemporal epilepsies are also satisfactory. Despite worldwide expansion during the recent decade, epilepsy surgery remains underutilized. Better understanding of advances in presurgical evaluation should reduce fears of epilepsy surgery and help to select patients who could achieve complete seizure control or significant amelioration after surgery.
Keywords: pharmacoresistant epilepsy; epileptogenic zone; epilepsy surgery pharmacoresistant epilepsy; epileptogenic zone; epilepsy surgery
MDPI and ACS Style

Gelžinienė, G.; Endzinienė, M.; Vaičienė, N.; Magistris, M.R.; Seeck, M. Presurgical evaluation of epilepsy patients. Medicina 2008, 44, 585.

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