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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

The prevalence of the metabolic syndrome components and their combinations in men and women with acute ischemic syndromes

1
Department of Cardiology
2
Institute of Cardiology, Kaunas University of Medicine, Lithuania
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Author to whom correspondence should be addressed.
Medicina 2008, 44(7), 521; https://doi.org/10.3390/medicina44070067
Received: 4 January 2008 / Accepted: 12 June 2008 / Published: 17 June 2008
During the last decade, it has been shown that the metabolic syndrome and its different components – arterial hypertension (AH), abdominal obesity (AO), diabetes mellitus (DM), atherogenic hypertriglyceridemia (HTG), and/or low concentration of high-density lipoprotein cholesterol (HDL-C)) – increase the risk of cardiovascular diseases. There is increasing evidence that the incidence of the metabolic syndrome and the distribution of its components in combinations in the general male and female population differ. The aim of our study was to determine the incidence of the metabolic syndrome in men and women with acute ischemic syndromes and to evaluate the distribution of the metabolic syndrome component combinations in the presence of the metabolic syndrome.
Contingent and methods
. The study included 2756 patients (1670 males and 1086 females) with acute ischemic syndromes (1997 with myocardial infarction and 759 with unstable angina pectoris), in whom all five components of the metabolic syndrome were assessed. Women were significantly older than men (68.1±9.5 vs. 60.2±11.8 years, P<0.001). The metabolic syndrome was found (according to modified NCEP III) in 1641 (59.5%) patients (in 70.2% of females and in 52.6% of males, P<0.001). The most common components in both men and women were AH andAO(94.0%vs. 95.9%and 86.4%vs. 84.5%, respectively). HTGwas significantlymore common in men than in women (80.0% vs. 73.0%, P<0.001), while decreased HDL-C concentration was more common in women (82.8% and 59.2%, P<0.001). The DM component, detected in more than one-third of patients with acute ischemic syndromes, was significantly more common in women than in men (39.2% vs. 33.1%, P<0.05). Combinations of three components were significantly more common in men than in women, while combinations of four–five components were more common in women (55.6% vs. 41.4%, P<0.001; and 58.6% vs. 44.4%, P<0.01). The most common combination of three components in men was AH+AO+HTG and in women – AH+AO+lowHDL-C; themost common combination of four components in bothmen and women was AH+AO+HTG+low HDL-C.
Conclusion
. In the metabolic syndrome, the differences between the components of atherogenic dyslipidemia in patients with acute ischemic syndromes were related to the patients’ gender: men significantly more frequently had increased TG concentration and women – decreased HDLC concentration; this is the problem to be addressed in further studies of dyslipidemia.
Keywords: metabolic syndrome components; acute ischemic syndromes metabolic syndrome components; acute ischemic syndromes
MDPI and ACS Style

Žaliūnas, R.; Šlapikas, R.; Babarskienė, R.; Šlapikienė, B.; Lukšienė, D.; Milvidaitė, I.; Laukaitienė, J. The prevalence of the metabolic syndrome components and their combinations in men and women with acute ischemic syndromes. Medicina 2008, 44, 521.

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