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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Comparison of postoperative results after implantation of hydrophilic acrylic or hydrophobic acrylic intraocular lens: Data of one-year prospective clinical study

1
Department of Eye Diseases
2
Institute for Biomedical Research, Kaunas University of Medicine, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2008, 44(12), 936; https://doi.org/10.3390/medicina44120117
Received: 19 May 2008 / Accepted: 5 December 2008 / Published: 10 December 2008
Objective. To evaluate and compare the impact of two sharp-edge optic foldable intraocular lenses (IOLs) of similar design made from different material (hydrophilic acrylic or hydrophobic acrylic) on visual function, anterior and posterior capsule opacification at one-year follow-up after cataract phacoemulsification.
Material and methods. Seventy-two eyes of 72 patients scheduled for cataract surgery were included in a prospective clinical study. Two foldable sharp-edge optic posterior chamber acrylic IOLs of similar design were used. Thirty-nine eyes of 39 patients received a single-piece hydrophilic acrylic (PC 511, Ophtec) IOL and 33 eyes of 33 patients – single-piece hydrophobic acrylic (AcrySof, SA60AT, Alcon) IOL. Visual acuity, anterior capsule opacification (ACO), capsulorrhexis/optic overlapping, and posterior capsule opacification (PCO) were evaluated. The intensity of ACO was assessed subjectively. PCO values in the entire IOL optic area and in the central 3-mm optic zone were assessed using a photographic image analysis system (EPCO 2000). The patients were examined at one year postoperatively.
Results.
There were no significant differences in best-corrected visual acuity and capsulorrhexis/optic overlapping between IOL types at 1-year follow-up after surgery. In the single-piece hydrophilic acrylic IOL group, the grade of ACO density was significantly higher in capsulorrhexis rim area (1.56±0.71 and 1.00±0.75) and in the capsule/optic area (1.62±0.67 and 1.00±0.75) (P<0.05). PCO values of the entire IOL optic area (0.12±0.13 and 0.024±0.02) as well as in the central 3-mm optic zone (0.06±0.11 and 0.001±0.003) was significantly higher in the single-piece hydrophilic acrylic IOL group one year postoperatively (P<0.05). In 33.3% of cases of the single-piece hydrophilic acrylic IOL group, contraction of haptics to IOL optics was present one year postoperatively, which was not present in any case of the single-piece hydrophobic acrylic IOL group.
Conclusions
. One-year follow-up after cataract surgery has shown a significant difference in ACO and PCO development comparing single-piece hydrophilic acrylic and single-piece hydrophobic acrylic intraocular lenses. The effect of hydrophobic acrylic foldable lenses on preventing anterior and posterior capsule opacification is mainly a result of the acrylic hydrophobic biomaterial.
Keywords: cataract phacoemulsification; anterior capsulorrhexis; anterior capsule opacification; posterior capsule opacification; hydrophobic acrylic intraocular lens; hydrophilic acrylic intraocular lens cataract phacoemulsification; anterior capsulorrhexis; anterior capsule opacification; posterior capsule opacification; hydrophobic acrylic intraocular lens; hydrophilic acrylic intraocular lens
MDPI and ACS Style

Žemaitienė, R.; Špečkauskas, M.; Glebauskienė, B.; Jašinskas, V. Comparison of postoperative results after implantation of hydrophilic acrylic or hydrophobic acrylic intraocular lens: Data of one-year prospective clinical study. Medicina 2008, 44, 936.

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