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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Characteristics of gender-related circadian arterial blood pressure in healthy adolescents

Children Hospital
Institute of Oncology, Vilnius University
Department of Children Diseases
Department of Theoretical and Clinical Pharmacology, Kaunas University of Medicine, Lithuania
Author to whom correspondence should be addressed.
Medicina 2008, 44(10), 768;
Received: 5 March 2008 / Accepted: 3 October 2008 / Published: 8 October 2008
Objective. To define 24-h characteristics of arterial blood pressure in healthy adolescent girls and boys; to determine gender-related differences of blood pressure, its circadian pattern.
Material and methods
. The 24-h blood pressure was monitored hourly in healthy girls (n=22, without no account for the menstrual cycle phase) and boys (n=22). Additionally, blood pressure of adolescent girls (n=15) was examined during different phases of their menstrual cycle (follicular, ovulation, and luteal). Blood pressure was monitored with an auto-cuff automatic outpatient blood pressure monitor.
. Investigation showed gender-related differences in 24-h blood pressure. Study results revealed the circadian blood pressure rhythm characterized by a period of low values during nighttime and an early morning increase in both adolescent groups. Nocturnal systolic blood pressure was higher (P<0.05) in boys than in girls in all phases of their menstrual cycle. Diurnal systolic blood pressure in boys was higher than in girls in their follicular phase (P<0.05). The day and night blood pressure differed between boys and girls (P<0.05). A dipping blood pressure pattern as a decrease in mean nighttime blood pressure as compared with mean daytime blood pressure was defined: 10.02±6.7% in girls (n=22) and 13±6.3% in boys (n=22), without genderrelated differences (P>0.05). There were no differences in blood pressure dipping among girls’ groups in different menstrual cycle phases (P>0.05). Adolescent boys showed a significant positive correlation between their mean diurnal blood pressure and height (P<0.05).
Conclusion. The study proved gender-related arterial blood pressure differences in healthy adolescents. The results demonstrate the gender-specific circadian blood pressure rhythm pattern in both gender groups.
Keywords: adolescent; blood pressure; gender-related differences; menstrual cycle adolescent; blood pressure; gender-related differences; menstrual cycle
MDPI and ACS Style

Drižienė, Ž.; Jakutienė, E.; Stakišaitis, D.; Pundzienė, B.; Sveikata, A. Characteristics of gender-related circadian arterial blood pressure in healthy adolescents. Medicina 2008, 44, 768.

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