Next Article in Journal
Prognostic value of reticulocyte hemoglobin content to diagnose iron deficiency in 6–24-month-old children
Previous Article in Journal
Impact of electrical shock waveform and paddle positions on efficacy of direct current cardioversion for atrial fibrillation
Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Evaluation of biologically active compounds in roots and rhizomes of Rhodiola rosea L. cultivated in Lithuania

1
Department of Pharmaceutical Technology and Social Pharmacy, Kaunas University of Medicine, Lithuania
2
Department of Pharmacognosy
3
Department of Pharmaceutical Technology, Medical University of Gdansk, Poland
*
Author to whom correspondence should be addressed.
Medicina 2007, 43(6), 487; https://doi.org/10.3390/medicina43060061
Received: 23 February 2007 / Accepted: 11 June 2007 / Published: 16 June 2007
Salidroside and rosavins (rosavin, rosarin, and rosin), biologically active compounds of Rhodiola rosea L., were analyzed in dried roots and rhizomes of the plants cultivated in Lithuania and naturally growing in Altai geographical region in Russian Federation. The quantitative analysis of the aqueous-ethanolic extracts prepared by percolation was performed employing solid-phase extraction and thin-layer chromatography followed by densitometric determination. Similar amounts of salidroside were found in the extracts (1.35–1.62 mg/mL), irrespective of the origin of the crude plant; however, the differences in the profile of rosavins were substantial with higher content of total rosavins in the extracts obtained from the plant cultivated in Lithuania (7.4 vs. 4.2 mg/mL). It was demonstrated that extracts prepared with 70% (v/v) ethanol contained low concentration of salidroside (0.16–0.17 mg/mL), while the extraction of rosavins with 70% (v/v) ethanol was more efficient compared to 40% (v/v) ethanol.
Keywords: salidroside; rosavins; solid-phase extraction and thin-layer chromatography; Rhodiola rosea L. salidroside; rosavins; solid-phase extraction and thin-layer chromatography; Rhodiola rosea L.
MDPI and ACS Style

Kučinskaitė, A.; Pobłocka-Olech, L.; Krauze-Baranowska, M.; Sznitowska, M.; Savickas, A.; Briedis, V. Evaluation of biologically active compounds in roots and rhizomes of Rhodiola rosea L. cultivated in Lithuania. Medicina 2007, 43, 487.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop