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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Outpatient methadone maintenance treatment program Quality of life and health of opioid-dependent persons in Lithuania

1
Department of Preventive Medicine, Kaunas University of Medicine
2
Department of Psychiatry, Vilnius University, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2007, 43(3), 235; https://doi.org/10.3390/medicina43030029
Received: 20 April 2006 / Accepted: 15 November 2006 / Published: 20 November 2006
Background. The evaluation of quality of life and self-perceived health represents an assessment of the impact of treatment on patient functioning and well-being.
Objective
. Our aim was to explore the impact of methadone maintenance treatment on quality of life and self-perceived health of opioid-dependent persons in Lithuania.
Methods. A total of 102 opioid-dependent patients were recruited in the study. A prospective follow-up study design was used. To assess quality of life, the WHOQOL-BREF 26-item version was used. The impact of methadone maintenance treatment on self-perceived health was assessed by Opiate Treatment Index (OTI).
Results
. Following 6 months of methadone maintenance treatment, significant improvements in physical (P=0.004), psychological (P=0.004), and environmental (P=0.048) components of quality of life were observed; no statistically significant improvements were found in social component of quality of life. Study participants reported lower rates of medical morbidity associated with injection (P<0.001), cardiorespiratory (P=0.034), musculoskeletal (P<0.001), neurological (P=0.013), gastrointestinal (P<0.001), and general health (P<0.001).
Conclusions
. Methadone maintenance treatment substantially reduces morbidity associated with opioid dependence and improves the quality of life of patients.
Keywords: opioid dependence; methadone; maintenance treatment; health; quality of life opioid dependence; methadone; maintenance treatment; health; quality of life
MDPI and ACS Style

Padaiga, Ž.; Subata, E.; Vanagas, G. Outpatient methadone maintenance treatment program Quality of life and health of opioid-dependent persons in Lithuania. Medicina 2007, 43, 235.

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