The role of D-dimer in the diagnosis of strangulated small-bowel obstruction
Methods. A prospective study of 53 patients with small-bowel obstruction was conducted. Strangulated obstruction was present in 15 (28.3%) patients. Eight (53%) had intestinal necrosis, while 7 (47%) reversible ischemia. The blood samples were taken and analyzed with NycoCard Reader method with monoclonal antibodies specific for D-dimer neoantigens.
Results. In the presence of intestinal necrosis, there was a higher D-dimer level found than in the cases with reversible ischemia or simple small-bowel obstruction, although this difference did not reach statistically significant level. The D-dimer test had a sensitivity of 60%, specificity of 68%, positive predictive value of 43%, and negative predictive value of 81% in diagnosing strangulated obstruction.
Conclusion. In present series, D-dimer test was neither sensitive nor specific in diagnosing strangulation.
Boguševičius, A.; Grinkevičius, A.; Maleckas, A.; Pundzius, J. The role of D-dimer in the diagnosis of strangulated small-bowel obstruction. Medicina 2007, 43, 850.
Boguševičius A, Grinkevičius A, Maleckas A, Pundzius J. The role of D-dimer in the diagnosis of strangulated small-bowel obstruction. Medicina. 2007; 43(11):850.Chicago/Turabian Style
Boguševičius, Algirdas; Grinkevičius, Arūnas; Maleckas, Almantas; Pundzius, Juozas. 2007. "The role of D-dimer in the diagnosis of strangulated small-bowel obstruction." Medicina 43, no. 11: 850.