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Special Issue Information

Dear Colleagues,

The plant kingdom is one of the richest reservoirs of organic compounds of different structures, called secondary metabolites, which are quite always unique for each species. Among the thousands of secondary metabolites present in plants, phenolic compounds are one of the wider classes synthetized. To this class of compounds belong those that possess one phenol ring, such as phenolic acids and phenolic alcohols, or more than one phenol ring, which are named polyphenols. They are considered excellent antioxidants and are related to the diminishment of risks of important chronic diseases. In addition, industrial agri-food wastes can be still rich in polyphenols and their recovery through different extraction techniques would help to reduce the environmental impact of these wastes. At the same time, they could have potential applications in the food, cosmetic, and pharmaceutical industries, contributing to the circular bio-economy.

Different extraction techniques can be used for the recovery of polyphenols and more efficient unconventional extraction techniques are also applied such as microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), pulse-elec. Field extraction (PEFE), etc.

This Special Issue aims to collect original research articles and reviews dealing with the identification, extraction and quantification of bioactive phenolic and polyphenolic compounds in food and natural products. Papers focused on new analytical methodologies and sensor development for bioactive polyphenol identification will also be considered, as well as papers on new extraction techniques and biological activity studies.

I look forward to receiving your contributions.

Prof. Dr. Cristina Forzato
Guest Editor

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Published Papers (1 paper)

Research

18 pages, 2968 KiB

Open AccessArticle

Improvement of Bioactive Polyphenol Accumulation in Callus of Salvia atropatana Bunge

by Izabela Grzegorczyk-Karolak, Wiktoria Ejsmont, Anna Karolina Kiss, Przemyslaw Tabaka, Wiktoria Starbała and Marta Krzemińska

Molecules 2024, 29(11), 2626; https://doi.org/10.3390/molecules29112626 - 3 Jun 2024

Viewed by 134

Abstract

Callus cultures of the Iranian medicinal plant Salvia atropatana were initiated from three-week-old seedlings on Murashige and Skoog (MS) medium supplemented with α-naphthaleneacetic acid (NAA) and various cytokinins. Although all tested hormonal variants of the medium and explant enabled callus induction, the most promising growth was noted for N-(2-chloro-4-pyridyl)-N′-phenylurea (CPPU)-induced calli. Three lines obtained on this medium (cotyledon line-CL, hypocotyl line—HL, and root line—RL) were preselected for further studies. Phenolic compounds in the callus tissues were identified using UPLC–MS (ultra-performance liquid chromatography–mass spectrometry) and quantified with HPLC (high-performance liquid chromatography). All lines exhibited intensive growth and contained twelve phenolic acid derivatives, with rosmarinic acid predominating. The cotyledon-derived callus line displayed the highest growth index values and polyphenol content; this was exposed to different light-emitting diodes (LED) for improving biomass accumulation and secondary metabolite yield. Under LED treatments, all callus lines exhibited enhanced RA and total phenolic content compared to fluorescent light, with the highest levels observed for white (48.5–50.2 mg/g dry weight) and blue (51.4–53.9 mg/g dry weight) LEDs. The selected callus demonstrated strong antioxidant potential in vitro based on the 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric reducing antioxidant power (FRAP) tests. Our findings confirm that the S. atropatana callus system is suitable for enhanced rosmarinic acid production; the selected optimized culture provide high-quality plant-derived products. Full article

(This article belongs to the Special Issue Bioactive Phenolic and Polyphenolic Compounds, Volume III)

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