Advances in Molecular Research of Diabetes Mellitus

Dear Colleagues,

Over the last few years, we have witnessed a dramatic increase in the incidence and prevalence of diabetes mellitus (DM), one of the most common non-communicable diseases worldwide. Patients mostly suffer from the two major forms of DM, type 1, wherein autoimmunity-driven pancreatic β-cell death results in a lack of insulin, and type 2, characterized by malfunctioning cellular sensing and response to insulin and/or defective insulin secretion, eventually leading to hyperglycaemia. The less common forms, such as monogenic diabetes, mitochondrial diabetes, rare syndrome-associated diabetes, etc., are present in the rest of the patient population. Individuals who exhibit persistent hyperglycaemia may develop systemic complications such as microangiopathy and macroangiopathy, as well as peripheral neuropathy. Longstanding endeavours in this research field have focused on clarifying the pathophysiological mechanisms linked with DM manifestation and progression to explore the natural history of DM and to find targets able to halt its broad-spectrum comorbidities.

As an effort to provide new findings in this field, this Special Issue will be devoted to the molecular basis of diabetes mellitus. We seek high-quality research papers addressing the molecular aspects of every type of DM. Researchers from a wide range of professional backgrounds are welcome to contribute. Original research papers and state-of-the-art reviews will be considered.

Dr. Anastasia Thanopoulou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• diabetes

• insulin resistance
• adiposity
• complications
• genes