Recent Advances in Nanobiocatalysts Design, and Their Industrial and Biomedical Applications

A special issue of Catalysts (ISSN 2073-4344). This special issue belongs to the section "Biocatalysis".

Deadline for manuscript submissions: closed (15 February 2024) | Viewed by 1666

Special Issue Editors


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Guest Editor
Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Interests: catalysts; enzymology; computational biology; biochemistry

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Guest Editor
Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA
Interests: cancer metabolism; folate signalling; antibody–drug conjugates; drug combinations

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Guest Editor
Qatar Biomedical Research Institute (QBRI), HBKU, Doha, Qatar
Interests: enzyme structure and mechanism; structural biology; molecular chaperones; transcription factors; cancer metabolism

Special Issue Information

Dear Colleagues,

Biocatalysts are defined as the enzymes which in a purified form, a cell lysate or as whole cells convert a molecular substance into a product. Biocatalysts or enzymes, unlike metal catalysts, are biodegradable and easily replenished through inexpensive and environmentally benign fermentation processes. Modern-day techniques such as genetic engineering, directed evolution, rational protein engineering, computational enzyme design, and metagenomics has paved the way to produce enzymes of diverse functionality. Furthermore, advances in nanotechnology have shown the way forward to generate nano-scale materials with tunable physicochemical properties. Nanomaterials are often used as a support for the immobilization of enzymes to increase their surface area. The amalgamation of nanotechnology and biocatalysis technology holds promising potential in industrial as well as biomedical applications, such as biosensors, biofuel cells, bioelectronics, biodiesel production, biomedical diagnostics, etc. Thus, this Special Issue shall provide a platform to discuss the recent development of nanobiocatalysis and their application in biomedical as well as industrial sectors.

The current Special Issue focuses on the synthesis, characterization, and application of biocatalysts for industrial and biomedical applications. We invite experimental as well as theoretical studies such as research articles, reviews, short communications, and perspectives for submission.

Dr. Md Tabish Rehman
Dr. Gulam Mohmad Rather
Dr. Zeyaul Islam
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • enzyme immobilization
  • industrial biocatalysis
  • biomedical/therapeutic biocatalysis
  • smart biocatalysts
  • nanotechnology
  • metal–organic frameworks
  • enzyme engineering
  • enzyme bioinformatics
  • proteins and peptides
  • chemical reaction
  • biotransformation
  • green synthesis

Published Papers (1 paper)

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Review

24 pages, 1866 KiB  
Review
Green Synthesis of Biocatalysts Based on Nanocarriers Promises an Effective Role in Pharmaceutical and Biomedical Fields
by Doaa S. R. Khafaga, Mohamed G. Radwan, Ghazala Muteeb, Mohammad Aatif and Mohd Farhan
Catalysts 2023, 13(11), 1448; https://doi.org/10.3390/catal13111448 - 17 Nov 2023
Cited by 3 | Viewed by 1321
Abstract
Nanobiocatalysts (NBCs) are a promising new class of biocatalysts that combine the advantages of enzymes and nanomaterials. Enzymes are biological catalysts that are highly selective and efficient, but they can be unstable in harsh environments. Nanomaterials, on the other hand, are small particles [...] Read more.
Nanobiocatalysts (NBCs) are a promising new class of biocatalysts that combine the advantages of enzymes and nanomaterials. Enzymes are biological catalysts that are highly selective and efficient, but they can be unstable in harsh environments. Nanomaterials, on the other hand, are small particles with unique properties that can improve the stability, activity, and selectivity of enzymes. The development of NBCs has been driven by the need for more sustainable and environmentally friendly bioprocessing methods. Enzymes are inherently green catalysts, but they can be expensive and difficult to recover and reuse. NBCs can address these challenges by providing a stable and reusable platform for enzymes. One of the key challenges in the development of NBCs is the immobilization of enzymes on nanomaterials. Enzyme immobilization is a process that attaches enzymes to a solid support, which can protect the enzymes from harsh environments and make them easier to recover and reuse. There are many different methods for immobilizing enzymes, and the choice of method depends on the specific enzyme and nanomaterial being used. This review explores the effective role of NBCs in pharmaceutical and biomedical fields. Full article
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