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2 articles matched your search query. Search Parameters:
Authors = Tsun-Tai Yeh

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Open AccessArticle Briacavatolides D–F, New Briaranes from the Taiwanese Octocoral Briareum excavatum
by , and
Mar. Drugs 2012, 10(9), 2103-2110; doi:10.3390/md10092103
Received: 17 August 2012 / Revised: 18 September 2012 / Accepted: 18 September 2012 / Published: 24 September 2012
Cited by 6 | Viewed by 2025 | PDF Full-text (956 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by
[...] Read more.
In the continued search for novel bioactive substances from the Taiwanese octocoral Briareum excavatum collected at Orchid Island, three new briarane-type diterpenoids, briacavatolides D–F (1–3) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NMR spectroscopic analysis and physical data. The anti-HCMV (human cytomegalovirus) activity of 1–3 and their cytotoxicity against selected cancer cell lines were evaluated. Full article
Open AccessArticle Briacavatolides A–C, New Briaranes from the Taiwanese Octocoral Briareum excavatum
by , , and
Mar. Drugs 2012, 10(5), 1019-1026; doi:10.3390/md10051019
Received: 13 March 2012 / Revised: 9 April 2012 / Accepted: 28 April 2012 / Published: 2 May 2012
Cited by 10 | Viewed by 2064 | PDF Full-text (1021 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
In order to search for novel bioactive substances from marine organisms, we have investigated the organic extracts of the Taiwanese octocoral Briareum excavatum collected at Orchid Island. Three new briarane-type diterpenoids, briacavatolides A–C (1–3) as well as two known
[...] Read more.
In order to search for novel bioactive substances from marine organisms, we have investigated the organic extracts of the Taiwanese octocoral Briareum excavatum collected at Orchid Island. Three new briarane-type diterpenoids, briacavatolides A–C (1–3) as well as two known briaranes, briaexcavatolide U (4) and briaexcavatin L (5) were isolated from the acetone extract. The structures of these compounds were elucidated by extensive NMR spectroscopic analysis and physical data. The anti-HCMV (human cytomegalovirus) activity of 1–5 and their cytotoxicity against selected cancer cell lines were evaluated. Full article
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