http://www.mdpi.com/journal/molecules/special_issues/heteroaromatic-chemistry/ Dear Colleagues, Aromatic heterocyclic chemistry is a vast subject that has been and continues to be a focus of interest in both the academic and industrial worlds. Aromatic heterocycles are found in nature (for example in nucleic acids and indole alkaloids) and have been widely used as herbicides, fungicides, insecticides, dyes, and as pharmaceuticals. The cyclic structure of these compounds must contain at least one heteroatom (usually N, O or S) and may vary in size (5 and 6-membered heterocyclic structures are most common). The aromaticity of these compounds can be viewed in two different ways: (a) it is inherited (for example aniline) because the structure meets all the standard conditions associated with aromaticity, or (b) it is earned (for example pyrrole) via the delocalization of a lone pair of electrons from the heteroatom. This special issue of Molecules will consider any submissions associated with heteroaromatic chemistry (including but not limited to: biological, theoretical and mechanistic studies). However, the primary focus of this special issue is related to the synthesis and reactions of heteroaromatic compounds. Dr. Guy L. Plourde Guest Editor Related Special Issues Advances in Heterocyclic Chemistry in Molecules Submission All papers should be submitted to molecules@mdpi.com with copy to the guest editor. To be published continuously until the deadline and papers will be listed together at the special websites. Submitted papers should not have been previously published nor be currently under consideration for publication elsewhere. All papers are refereed through a peer review process. A guide for authors, sample copies and other relevant information for submitting papers are available on the Instructions for Authors page. Molecules is an international peer-reviewed monthly journal published by MDPI. Please visit the Instructions for Authors page before submitting a paper. Open Access publication fees are 800 CHF per paper. English correction fees (250 CHF) will be added in certain cases (1050 CHF per paper for those papers that require extensive additional formatting and/or English corrections). http://www.mdpi.com/1420-3049/14/12/5169/ CuO/AB was found to be a simple and efficient catalyst for the N-arylation of a variety of nitrogen-containing heterocycles, giving the products in excellent yields. http://www.mdpi.com/1420-3049/14/12/5169/ Thu, 10 Dec 2009 00:00:00 CET Molecules 2009-12-10 14 12 Communication 5169 5178 1420-3049 Highly Efficient and Reusable Copper-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles with Aryl Halides 2009-12-10 doi: 10.3390/molecules14125169 A Young Kim Hyun Ju Lee Ji Chan Park Hyunju Kang Haesik Yang Hyunjoon Song Kang Hyun Park http://www.mdpi.com/1420-3049/14/11/4634/ A new process is described for preparing very pure linear alkanethiols and linear α,ω-alkanedithiols using a sequential alkylation of the title compound, followed by a ring closure to quantitatively give the corresponding 3-methyl[1,3]thiazolo[3,2-a]-[3,1]benzimidazol-9-ium salt and the alkanethiol derivative under mild conditions. The alkanethiol and the heteroaromatic salt are easily separated by a simple extraction process. The intermediate thiazolium quaternary salts resulting from the first reaction step can be isolated in quantitative yields, affording an odourless protected form of the thiols. http://www.mdpi.com/1420-3049/14/11/4634/ Thu, 12 Nov 2009 00:00:00 CET Molecules 2009-11-12 14 11 Article 4634 4643 1420-3049 3-(2-Aminophenyl)-4-methyl-1,3-thiazole-2(3H)-thione as an Ecofriendly Sulphur Transfer Agent to Prepare Alkanethiols in High Yield and High Purity 2009-11-12 doi: 10.3390/molecules14114634 Mohammed Amine Mehdid Ayada Djafri Christian Roussel Federico Andreoli http://www.mdpi.com/1420-3049/14/10/3952/ An efficient and practical method for the synthesis of indolyl-nitroalkane derivatives catalyzed by N-bromosuccinimide is described. The generality of this method was demonstrated by synthesizing an array of diverse 3-substituted indole derivatives by the reaction of different β-nitrostyrenes with various substituted indoles. Simple reaction conditions accompanied by good yields of indolyl-nitroalkanes are the merits of this methodology. http://www.mdpi.com/1420-3049/14/10/3952/ Fri, 09 Oct 2009 00:00:00 CEST Molecules 2009-10-09 14 10 Article 3952 3963 1420-3049 An Efficient Method for the N-Bromosuccinimide Catalyzed Synthesis of Indolyl-Nitroalkanes 2009-10-09 doi: 10.3390/molecules14103952 Chun-Wei Kuo Chun-Chao Wang Hu-Lin Fang B. Rama Raju Veerababurao Kavala Pateliya Mujjamil Habib Ching-Fa Yao http://www.mdpi.com/1420-3049/14/8/3073/ A variety of heteroaromatic compounds, such as substituted pyridines, pyrazoles, indoles, 2-substituted imidazoles, 2-substituted imidazoles, 2-arylbenzazoles and pyrimidin-2(1H)-ones are synthesized by oxidative aromatization using the activated carbon and molecular oxygen system. Mechanistic study focused on the role of activated carbon in the synthesis of 2-arylbenzazoles is also discussed. In the final section, we will disclose the efficient synthesis of substituted 9,10-anthracenes via oxidative aromatization. http://www.mdpi.com/1420-3049/14/8/3073/ Fri, 14 Aug 2009 00:00:00 CEST Molecules 2009-08-14 14 8 Review 3073 3093 1420-3049 Synthesis of Heteroaromatic Compounds by Oxidative Aromatization Using an Activated Carbon/Molecular Oxygen System 2009-08-14 doi: 10.3390/molecules14083073 Yuka Kawashita Masahiko Hayashi http://www.mdpi.com/1420-3049/14/8/2747/ The perovskite-type oxide catalyst LaFe1-xCuxO3 (x=0, 0.1, 0.2) was prepared by the sol–gel method, and tested as a catalyst in the wet aerobic oxidation (WAO) of lignin into aromatic aldehydes. The lignin conversion and the yield of each aromatic aldehyde were significantly enhanced in the catalytic process, compared with the non-catalyzed process. Moreover, it was shown that the stability of activity and structure of LaFe1-xCuxO3 (x=0, 0.1, 0.2) remained nearly unchanged after a series of successive recyclings of the catalytic reactions, indicating it was an efficient and recyclable heterogeneous catalyst for the conversion of lignin into aromatic aldehydes in the WAO process. http://www.mdpi.com/1420-3049/14/8/2747/ Mon, 27 Jul 2009 00:00:00 CEST Molecules 2009-07-27 14 8 Article 2747 2757 1420-3049 Wet Aerobic Oxidation of Lignin into Aromatic Aldehydes Catalysed by a Perovskite-type Oxide: LaFe1-xCuxO3 (x=0, 0.1, 0.2) 2009-07-27 doi: 10.3390/molecules14082747 Junhua Zhang Haibo Deng Lu Lin