http://www.mdpi.com/journal/marinedrugs/special_issues/halophilic-bacteria/ Dear Colleagues, Biochemical and cellular analyses of halophilic microbes are often more difficult because of the high internal salt concentrations of these cells, usually equivalent to the external salt levels (2-5 M). The presence of salt often interferes with standard analytical methods (e.g. mass spectroscopy), and for this issue, we encourage the submission of manuscripts relating to halophilic microbes, particularly extremely halophilic microbes, and where there has been shown to be an improvement in their analysis by new or modified techniques that overcome the problems of salt. Examples of the types of studies include, electron microscopy of extreme halophiles, assay of bioactive compounds, purification of halophilic proteins, recovery of cytoplasmic metabolites free of salt, etc. Prof. Dr. Michael L. Dyall-Smith Guest Editor Submission All manuscripts should be submitted to marinedrugs@mdpi.com with a copy to the Guest Editor. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed Open Access monthly journal published by MDPI. Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this Open Access journal is 1400 CHF per accepted paper.