Effect of Baicalin-Aluminum Complexes on Fecal Microbiome in Piglets
Abstract
:1. Introduction
2. Results
2.1. BBA Significantly Reduced the Diarrhea Rates of Piglets
2.2. Overall Structural Modulation of Gut Microbiome Following Treatment with BBA
2.3. The Effect of BBA on Modulation of Important Phylotypes of Gut Microbiome
2.4. The Effect of BBA on Modulation of Genes Expression of Gut Microbiome
3. Discussion
4. Materials and Methods
4.1. Drugs
4.2. Collection of Stool
4.3. DNA Extraction
4.4. DNA Library Construction and Sequencing
4.5. Metagenomic Analysis
4.6. Statistical Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Acknowledgments
Conflicts of Interest
References
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Samples | Raw Reads | Clean Reads | Clean Ratio (%) | Mapped Ratio (%) |
---|---|---|---|---|
Treated with BAA | 89,537,684 ± 5,405,796.2 | 87,247,590.3 ± 5,144,406.2 | 94.9 ± 0.2 | 99.1 ± 0.1 |
Untreated | 103,588,655.3 ± 13,288,842.4 | 100,319,056.3 ± 12,734,141.2 | 92.6 ± 0.2 | 99.0 ± 0.1 |
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Fu, S.; Zhuang, F.; Guo, L.; Qiu, Y.; Xiong, J.; Ye, C.; Liu, Y.; Wu, Z.; Hou, Y.; Hu, C.-A.A. Effect of Baicalin-Aluminum Complexes on Fecal Microbiome in Piglets. Int. J. Mol. Sci. 2019, 20, 2390. https://doi.org/10.3390/ijms20102390
Fu S, Zhuang F, Guo L, Qiu Y, Xiong J, Ye C, Liu Y, Wu Z, Hou Y, Hu C-AA. Effect of Baicalin-Aluminum Complexes on Fecal Microbiome in Piglets. International Journal of Molecular Sciences. 2019; 20(10):2390. https://doi.org/10.3390/ijms20102390
Chicago/Turabian StyleFu, Shulin, Feng Zhuang, Ling Guo, Yinsheng Qiu, Jianglin Xiong, Chun Ye, Yu Liu, Zhongyuan Wu, Yongqing Hou, and Chien-An Andy Hu. 2019. "Effect of Baicalin-Aluminum Complexes on Fecal Microbiome in Piglets" International Journal of Molecular Sciences 20, no. 10: 2390. https://doi.org/10.3390/ijms20102390