Special Issue "Antiviral Innate Immunity"

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A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Antivirals & Vaccines".

Deadline for manuscript submissions: closed (28 February 2011)

Special Issue Editor

Guest Editor
Prof. Dr. John Guatelli
Division of Infectious Diseases, School of Medecine, University of California, San Diego, 9500 Gilman Drive # 0679 La Jolla, CA 92093, USA
Website: http://id.ucsd.edu/faculty/guatelli.shtml
E-Mail: jguatelli@ucsd.edu

Special Issue Information

Dear Colleagues,

The innate immune response to viruses begins with the detection of viruses by the host, followed by the induction of cellular and molecular effectors with broad antiviral activity. Classically, effectors of the innate response include natural killer cells and the “antiviral state” induced by type I interferons. More recently, a number of intrinsic antiviral host proteins have been identified, including the so-called “restriction factors” that inhibit the replication of members of the retrovirus and other virus families. These factors have in some cases been linked to the innate response, specifically via their induction by interferon. Active issues in the field of antiviral innate immunity include the molecular and cellular mechanisms by which viruses are detected, the identification of new effectors of innate immunity including antiviral proteins and microRNAs, and the mechanisms by which viruses evade and antagonize the innate response. New functional screens and molecular genetic approaches are being used to explore these issues. These approaches seem likely to reveal novel aspects of the host-pathogen relationship and to dissect how these have affected the evolution of the host and viral genomes. We hope in this issue to capture the scope and flavor of these exciting developments.

Prof. Dr. John Guatelli
Guest Editor

Published Papers (6 papers)

Viruses 2011, 3(7), 1179-1203; doi:10.3390/v3071179
Received: 24 May 2011; in revised form: 28 June 2011 / Accepted: 29 June 2011 / Published: 14 July 2011
Show/Hide Abstract | Download PDF Full-text (335 KB)

Viruses 2011, 3(7), 1112-1130; doi:10.3390/v3071112
Received: 9 May 2011; in revised form: 26 June 2011 / Accepted: 29 June 2011 / Published: 11 July 2011
Show/Hide Abstract | Download PDF Full-text (290 KB)

Viruses 2011, 3(7), 1091-1111; doi:10.3390/v3071091
Received: 14 June 2011; in revised form: 23 June 2011 / Accepted: 24 June 2011 / Published: 8 July 2011
Show/Hide Abstract | Download PDF Full-text (528 KB)

Viruses 2011, 3(6), 920-940; doi:10.3390/v3060920
Received: 13 April 2011; in revised form: 27 May 2011 / Accepted: 2 June 2011 / Published: 23 June 2011
Show/Hide Abstract | Download PDF Full-text (362 KB)

Viruses 2011, 3(6), 906-919; doi:10.3390/v3060906
Received: 9 April 2011; in revised form: 4 June 2011 / Accepted: 9 June 2011 / Published: 23 June 2011
Show/Hide Abstract | Download PDF Full-text (315 KB)

Viruses 2011, 3(5), 520-540; doi:10.3390/v3050520
Received: 18 March 2011; in revised form: 19 April 2011 / Accepted: 28 April 2011 / Published: 6 May 2011
Show/Hide Abstract | Download PDF Full-text (596 KB)

Last update: 5 March 2014

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