Special Issue "Bio-devices and Materials"

Guest Editor
Dr. Hiroyuki Kudo
Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan
Website: http://www.tmd.ac.jp/i-mde/www/index-e.html
E-Mail:
Interests: biosensors; biochemical gas sensors; optical sensors; microsystems

Guest Editor
Prof. Dr. Kohji Mitsubayashi
Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan
Website: http://www.tmd.ac.jp/i-mde/www/index-e.html
E-Mail:
Interests: biomedical sensors for human monitoring; biochemical gas sensors; organic actuators

Editorial Advisor
Prof. Dr. Ulrich Simon
Inorganic Chemistry and Electrochemistry, RWTH Aachen University, Institute of Inorganic Chemistry, RWTH Aachen University, Landoltweg 1, 52056 Aachen, Germany
Website: http://www.ac.rwth-aachen.de/extern/ak-simon/ulrich_simon.htm
E-Mail:
Interests: synthesis of metal and metal oxide nanoparticles; synthesis of ionic conductors and of semiconducting nanostructures; electrical properties of nanomaterials; molecular self-assembly; biofunctional materials

Dear Colleagues,

Currently, sensors are recognized to be essential devices as interfaces of advanced information systems. Adding suitable functions to sensors is effective way to place and enhance value on information. For instance, an RFID reader which can scan every item in a shopping basket may provide a beneficial impact to customers, and continuous in-vivo biomonitoring with flexible and biocompatible sensors drastically improves the quality-of-life of patients and promotion of health by home healthcare. Fusion of new sensing methods, device technologies and advanced materials assumes important role in such “sensing” breakthroughs. This combined special issue entitled “Bio-devices and Materials” is intended to be a reflection of timely research topics, in the area of device technologies, methods and materials to open new window of sensing technologies.

Prof. Dr. Kohji Mitsubayashi
Dr. Hiroyuki Kudo
Guest Editors

Related Special Issues in other Journals

Bio-devices and Materials in Materials

Submission

• Biosensors
• Biomicrosystems
• Biomaterials
• Bioinstrumentations
• Polymers

Type of Paper: Article
Title: Bioactive Paper Biosensors with DNA Probes
Authors: M. Monsur Ali, Sergio Aguirre and Yingfu Li
Affiliation: Department of Biochemistry & Biomedical Sciences, Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Canada; E-mail: liying@mcmaster.ca (Y.L.)
Abstract: Developing diagnostic devices with paper substrates has attracted significant attentions later because paper-based materials are widely available, inexpensive and easy to dispose. Such devices are perceived to be particularly useful in the developing world where there aren't many sophisticated testing facilities staffed with highly qualified personnel. This article will discuss recent progresses in research on engineering bioactive papers for sensing applications that utilize various DNA probes (including DNA aptamers and DNAzymes) as molecular recognition elements (MREs). We will review methods for functionalizing paper surfaces with DNA probes and performances of some prototype bioactive papers that are designed to achieve target detection by simple fluorescent or colorimetric reporting mechanisms.

Type of Paper: Article
Title: Enzyme Immobilization Strategies and Electropolymerization Conditions to Control Sensitivity and Selectivity Parameters of a Polymer–Enzyme Composite Glucose Biosensor
Authors: Robert O'Neill et al.
Affiliation: UCD School of Chemistry & Chemical Biology, Science Centre (South), Belfield, Dublin 4, Ireland; E-mail: robert.oneill@ucd.ie
Abstract: Glucose biosensors were fabricated by immobilizing the enzyme glucose oxidase (GOx) on Pt cylinder wire electrodes (PtC), using three different methods: before, after or during the amperometric electrosynthesis of poly(ortho-phenylenediamine), PoPD, which also served as a permselective membrane. A number of selectivity parameters were used to identify the most successful design in terms of the balance between substrate sensitivity and interference blocking. Further optimization showed that fabrication of PtC/PoPD–GOx in the absence of added background electrolyte enhanced glucose selectivity 3-fold for this one-pot fabrication protocol.