Special Issue "Aptamer-Based Sensors"
A special issue of Sensors (ISSN 1424-8220).
Deadline for manuscript submissions: closed (30 October 2011)
Prof. Dr. Dipankar Sen
Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada V5A 1S6
Interests: DNA; RNA; ribozymes; deoxyribozymes; in vitro selection; catalysis; charge transfer; biosensors; photochemistry
Antibodies have been the traditional sensing platform underlying sensor design for the detection of biomedically and environmentally important “analytes”. However, in recent years, “aptamers”—DNA and RNA molecules with antibody-like properties of high-affinity and -specificity binding to analytes of interest—have started to assert themselves in the latest generations of sensors. In a number of ways, aptamers make excellent substitutes for antibodies: they are chemically stable, easily and inexpensively synthesized, and do not elicit a significant immune response if used in vivo. However, the isolation of a high-quality aptamer against a designated analyte does not in itself guarantee its usefulness as a biosensor; there is also the necessity for an effective transduction mechanism, such that analyte binding generates a quantifiable output (often optical or electronic) signal. This special issue of Sensors focuses on the variety of elegant approaches that have recently been taken to generate aptamer-based sensors—a new paradigm in analyte detection.
Prof. Dr. Dipankar Sen
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed Open Access monthly journal published by MDPI.
Sensors 2011, 11(9), 8953-8965; doi:10.3390/s110908953
Received: 21 July 2011; in revised form: 27 August 2011 / Accepted: 15 September 2011 / Published: 19 September 2011| Download PDF Full-text (791 KB) | Download XML Full-text
Article: Human Thrombin Detection Through a Sandwich Aptamer Microarray: Interaction Analysis in Solution and in Solid Phase
Sensors 2011, 11(10), 9426-9441; doi:10.3390/s111009426
Received: 29 July 2011; in revised form: 27 September 2011 / Accepted: 28 September 2011 / Published: 3 October 2011| Download PDF Full-text (469 KB) | Download XML Full-text
Article: A Conjugated Aptamer-Gold Nanoparticle Fluorescent Probe for Highly Sensitive Detection of rHuEPO-α
Sensors 2011, 11(11), 10490-10501; doi:10.3390/s111110490
Received: 24 August 2011; in revised form: 11 October 2011 / Accepted: 1 November 2011 / Published: 3 November 2011| Download PDF Full-text (709 KB) | Download XML Full-text
Sensors 2012, 12(2), 1181-1193; doi:10.3390/s120201181
Received: 19 December 2011; in revised form: 11 January 2012 / Accepted: 29 January 2012 / Published: 30 January 2012| Download PDF Full-text (366 KB) | Download XML Full-text
Sensors 2012, 12(2), 2136-2151; doi:10.3390/s120202136
Received: 11 January 2012; in revised form: 7 February 2012 / Accepted: 8 February 2012 / Published: 15 February 2012| Download PDF Full-text (960 KB) | Download XML Full-text
Last update: 13 December 2011