Special Issue "Aptamer-Based Sensors"

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A special issue of Sensors (ISSN 1424-8220).

Deadline for manuscript submissions: closed (30 October 2011)

Special Issue Editor

Guest Editor
Prof. Dr. Dipankar Sen
Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada V5A 1S6
Website: http://www.sfu.ca/mbb/faculty/sen/Sen_Lab/index.html
E-Mail: sen@sfu.ca
Interests: DNA; RNA; ribozymes; deoxyribozymes; in vitro selection; catalysis; charge transfer; biosensors; photochemistry

Special Issue Information

Dear Colleagues,

Antibodies have been the traditional sensing platform underlying sensor design for the detection of biomedically and environmentally important “analytes”. However, in recent years, “aptamers”—DNA and RNA molecules with antibody-like properties of high-affinity and -specificity binding to analytes of interest—have started to assert themselves in the latest generations of sensors. In a number of ways, aptamers make excellent substitutes for antibodies: they are chemically stable, easily and inexpensively synthesized, and do not elicit a significant immune response if used in vivo. However, the isolation of a high-quality aptamer against a designated analyte does not in itself guarantee its usefulness as a biosensor; there is also the necessity for an effective transduction mechanism, such that analyte binding generates a quantifiable output (often optical or electronic) signal. This special issue of Sensors focuses on the variety of elegant approaches that have recently been taken to generate aptamer-based sensors—a new paradigm in analyte detection.

Prof. Dr. Dipankar Sen
Guest Editor

Keywords

  • biosensor
  • aptamer
  • analyte
  • SELEX
  • transduction
  • fluorescence
  • absorbance
  • electronics

Published Papers (5 papers)

by , , , , ,  and
Sensors 2011, 11(9), 8953-8965; doi:10.3390/s110908953
Received: 21 July 2011; in revised form: 27 August 2011 / Accepted: 15 September 2011 / Published: 19 September 2011
Show/Hide Abstract | Cited by 4 | PDF Full-text (791 KB) | HTML Full-text | XML Full-text

by , ,  and
Sensors 2011, 11(10), 9426-9441; doi:10.3390/s111009426
Received: 29 July 2011; in revised form: 27 September 2011 / Accepted: 28 September 2011 / Published: 3 October 2011
Show/Hide Abstract | Cited by 5 | PDF Full-text (469 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , ,  and
Sensors 2011, 11(11), 10490-10501; doi:10.3390/s111110490
Received: 24 August 2011; in revised form: 11 October 2011 / Accepted: 1 November 2011 / Published: 3 November 2011
Show/Hide Abstract | Cited by 4 | PDF Full-text (709 KB) | HTML Full-text | XML Full-text

by ,  and
Sensors 2012, 12(2), 1181-1193; doi:10.3390/s120201181
Received: 19 December 2011; in revised form: 11 January 2012 / Accepted: 29 January 2012 / Published: 30 January 2012
Show/Hide Abstract | Cited by 12 | PDF Full-text (366 KB) | HTML Full-text | XML Full-text

by ,  and
Sensors 2012, 12(2), 2136-2151; doi:10.3390/s120202136
Received: 11 January 2012; in revised form: 7 February 2012 / Accepted: 8 February 2012 / Published: 15 February 2012
Show/Hide Abstract | Cited by 7 | PDF Full-text (960 KB) | HTML Full-text | XML Full-text
abstract graphic

Last update: 4 March 2014

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