Special Issue "Opto-Microfluidics for Bio Applications"


A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (15 July 2014)

Special Issue Editor

Guest Editor
Prof. Dr. Muthukumaran Packirisamy
Optical-Bio Microsystems Laboratory, Department of Mechanical and Industrial Engineering, CONCORDIA University, EV4-149, 1455 de Maisonneuve Blvd. W. Montreal, Quebec, H3G 1M8, Canada
Website: http://www.mie.concordia.ca/mems
E-Mail: pmuthu@alcor.concordia.ca
Interests: optical bioMEMS; MEMS for power applications; microphotonics; integration of microsystems and micro-nano integration

Special Issue Information

Dear Colleagues,

The area of Opto-Microfluidics involves microsystems formed by integrating microfluidics and microphotonics or micro optical or nano photonics elements for various applications. Some of the bio applications would include biosensing, bio diagnosis, cell sorting, cell counting, prognosis, etc. This special issue will address challenges involved with integration and application specific issues when micro photonics/micro optics/nano photonics elements are integrated.

Prof. Dr. Muthukumaran Packirisamy
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


  • microfluidics
  • microphotonics
  • nanophotonics
  • monolithic and hybrid integration
  • biosensing
  • bio diagnosis
  • cell analysis and characterization
  • micromachining/microfabrication/nanofabrication
  • modeling and verification

Published Papers (6 papers)

by , ,  and
Sensors 2014, 14(8), 15458-15479; doi:10.3390/s140815458
Received: 15 July 2014; in revised form: 14 August 2014 / Accepted: 15 August 2014 / Published: 21 August 2014
Show/Hide Abstract | PDF Full-text (1092 KB)

by , , ,  and
Sensors 2014, 14(8), 15400-15414; doi:10.3390/s140815400
Received: 16 July 2014; in revised form: 8 August 2014 / Accepted: 18 August 2014 / Published: 20 August 2014
Show/Hide Abstract | PDF Full-text (523 KB)
abstract graphic

by  and
Sensors 2014, 14(6), 10497-10513; doi:10.3390/s140610497
Received: 12 April 2014; in revised form: 24 May 2014 / Accepted: 9 June 2014 / Published: 13 June 2014
Show/Hide Abstract | PDF Full-text (1111 KB) | HTML Full-text | XML Full-text

by , , ,  and
Sensors 2014, 14(2), 2967-2980; doi:10.3390/s140202967
Received: 2 December 2013; in revised form: 4 January 2014 / Accepted: 27 January 2014 / Published: 13 February 2014
Show/Hide Abstract | PDF Full-text (691 KB) | HTML Full-text | XML Full-text | Supplementary Files

by , , , , ,  and
Sensors 2013, 13(12), 16075-16089; doi:10.3390/s131216075
Received: 18 September 2013; in revised form: 21 October 2013 / Accepted: 8 November 2013 / Published: 26 November 2013
Show/Hide Abstract | PDF Full-text (590 KB) | HTML Full-text | XML Full-text

by , ,  and
Sensors 2013, 13(8), 10711-10724; doi:10.3390/s130810711
Received: 9 July 2013; in revised form: 5 August 2013 / Accepted: 14 August 2013 / Published: 16 August 2013
Show/Hide Abstract | PDF Full-text (452 KB) | HTML Full-text | XML Full-text

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Type of Paper: Review
Title: Droplet Microfluidics for Chip Based Diagnostics
Authors: Karan V. I. S. Kaler 1,* and Ravi Prakash 2,†
Professor, Department of Electrical and Computer Engineering, University of Calgary, 2500 University Drive NW Calgary, AB – T2N 1N4, Canada; E-Mail: kaler@ucalgary.ca
2 University of Calgary, 2500 University Drive NW Calgary, AB – T2N 1N4, Canada; E-Mail: rprakash@ucalgary.ca
Abstract: Droplet Microfluidics (DMF) is a fluidic handling technology which enables precision control over dispensing and subsequent manipulation of droplets in the volume range of microliter to picoliter, on a micro fabricated device. There are several different droplet actuation methods, all of which can generate external stimuli, to either actively or passively control the shape and positioning of fluidic droplets over patterned substrates. In this review article, we focus on the operation and utility of electro-actuation based DMF devices which utilize one or more micro/nano patterned substrates to facilitate electric field based handling of chemical and/or biological samples. The underlying theory of DMF actuations, device fabrication methods and integration of optical and opto-electronic detectors are discussed in this review. Example applications of such electro-actuation based DMF devices have also been included, illustrating the various actuation methods and their utility in conducting chip based laboratory and clinical diagnostic assays.
Keywords: Droplet Microfluidics; Electro-actuation; Nucleic Acid; PCR; Immunoassays; qPCR; Photomultiplier Tube

Last update: 10 July 2014

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