Special Issue "Antituberculosis Drugs"
A special issue of Pharmaceuticals (ISSN 1424-8247).
Deadline for manuscript submissions: closed (31 August 2012)
Dr. Marcelo J. Nieto
Department of Pharmaceutical Sciences, School of Pharmacy, Southern Illinois University Edwardsville, Edwardsville, IL 62026-2000, USA
Interests: drug design; parallel synthesis; antibacterials; antimalarials; antimycobacterials; natural products; antivirals
Tuberculosis (TB), a disease cause by Mycobacterium tuberculosis (Mt), is one of the deadliest infectious diseases. Each year almost 2 million people die worldwide according to estimates from the World Health Organization (WHO). The treatment for tuberculosis is more than 30 years old and includes a multidrug approach during a long period of time (6-9 months). There are several resistant strains of Mt including multidrug (MDR) strains resistant to more than one first line drugs and extremely resistant strains (XDR), resistant to first and second line drugs. These strains have made Mt and TB very difficult to treat and eradicate. This special issue will focus on the biology of Mt, resistance, new targets, drug discovery and development, and clinical trials.
Dr. Marcelo J. Nieto
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed Open Access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 500 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- Mycobacterium tuberculosis
- TB resistance
- drug discovery
- mode of action
- clinical trials
- drug development
- opportunistic infections
Pharmaceuticals 2012, 5(7), 690-718; doi:10.3390/ph5070690
Received: 15 May 2012; in revised form: 12 June 2012 / Accepted: 21 June 2012 / Published: 28 June 2012| Download PDF Full-text (227 KB) | Download XML Full-text
Pharmaceuticals 2012, 5(8), 882-889; doi:10.3390/ph5080882
Received: 2 July 2012; in revised form: 24 July 2012 / Accepted: 3 August 2012 / Published: 23 August 2012| Download PDF Full-text (179 KB) | Download XML Full-text
Pharmaceuticals 2012, 5(9), 1021-1031; doi:10.3390/ph5091021
Received: 13 August 2012; in revised form: 10 September 2012 / Accepted: 11 September 2012 / Published: 17 September 2012| Download PDF Full-text (200 KB) | Download XML Full-text
Article: Metabolism and Pharmacokinetics of the Anti-Tuberculosis Drug Ethionamide in a Flavin-Containing Monooxygenase Null Mouse
Pharmaceuticals 2012, 5(11), 1147-1159; doi:10.3390/ph5111147
Received: 29 August 2012; in revised form: 8 October 2012 / Accepted: 16 October 2012 / Published: 25 October 2012| Download PDF Full-text (506 KB) | Download XML Full-text | Supplementary Files
Review: The Role of Transport Mechanisms in Mycobacterium Tuberculosis Drug Resistance and Tolerance
Pharmaceuticals 2012, 5(11), 1210-1235; doi:10.3390/ph5111210
Received: 27 August 2012; in revised form: 25 October 2012 / Accepted: 2 November 2012 / Published: 9 November 2012| Download PDF Full-text (517 KB) | Download XML Full-text
Last update: 18 May 2012