Special Issue "Gluten Related Disorders: People Shall not Live on Bread Alone"


A special issue of Nutrients (ISSN 2072-6643).

Deadline for manuscript submissions: 31 May 2015

Special Issue Editors

Guest Editor
Professor Carlo Catassi
Department of Pediatrics, Università Politecnica delle Marche, Ancona, Italy
E-Mail: c.catassi@univpm.it
Phone: +39 071 596 23 64
Fax: +39 071 36281
Interests: celiac disease; gluten-related disorders; gluten sensitivity; pediatric gastroenterology; pediatric nutrition
Guest Editor
Professor Alessio Fasano
Mucosal Immunology and Biology Research Center, Massachusetts General Hospital East, Building 114, 16th Street (Mail Stop 114-3503), Charlestown, MA 02129-4404, USA.
E-Mail: afasano@partners.org

Special Issue Information

Dear Colleagues,

Once upon a time, gluten was not a part of the human diet, and therefore, there were no gluten-related disorders.  With the advent of agriculture 10,000 years ago, the introduction of gluten-containing grains in the human diet created conditions for human diseases related to gluten exposure. These diseases, including celiac disease, non-celiac gluten sensitivity, and wheat allergy, have distinct pathophysiological mechanisms, serological markers, and long-term treatments, but similar, often overlapping clinical presentations.  Though current research strives to clarify the boundaries between these entities, their differences can be difficult to distinguish.

For a very long time, awareness of these disorders has been limited and, therefore, the epidemiology of gluten-related disorders has been a “work in progress”. New epidemiological studies have revealed that gluten-related disorders are not limited to European regions; rather, they are present worldwide.

After centuries of neglected attention to celiac disease and other forms of gluten reaction, now we are observing another interesting phenomenon that is generating great confusion among health care professionals.  Nearly 25% of Americans (many more than the projected 3 million CD patients in the U.S.) are reducing or cutting gluten from their diets. This remarkable trend in the general population reflects the misconception that gluten can be harmful for everybody and, therefore, should be avoided to stay healthy, to lose weight, or even to prevent severe diseases.

This Special Issue of Nutrients will contain contributions from leading experts in the field of gluten-related disorders that will help dissipate this confusion by sharing their evidence-based science, which will help the reader to distinguish facts from fantasies.

Prof. Carlo Catassi
Prof. Alessio Fasano
Guest Editors


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs).


  • celiac disease
  • autoimmunity
  • food antigen trafficking
  • gut permeability
  • microbiome
  • food sensitivities

Published Papers (3 papers)

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Displaying article 1-3
p. 2134-2144
by ,  and
Nutrients 2015, 7(4), 2134-2144; doi:10.3390/nu7042134
Received: 15 October 2014 / Accepted: 19 March 2015 / Published: 25 March 2015
Show/Hide Abstract | PDF Full-text (128 KB)
(This article belongs to the Special Issue Gluten Related Disorders: People Shall not Live on Bread Alone)
p. 1657-1671
by , , , ,  and
Nutrients 2015, 7(3), 1657-1671; doi:10.3390/nu7031657
Received: 20 January 2015 / Revised: 11 February 2015 / Accepted: 27 February 2015 / Published: 6 March 2015
Show/Hide Abstract | PDF Full-text (1082 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Gluten Related Disorders: People Shall not Live on Bread Alone)
p. 1565-1576
by , , , ,  and
Nutrients 2015, 7(3), 1565-1576; doi:10.3390/nu7031565
Received: 28 October 2014 / Revised: 5 February 2015 / Accepted: 11 February 2015 / Published: 27 February 2015
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(This article belongs to the Special Issue Gluten Related Disorders: People Shall not Live on Bread Alone)
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Last update: 5 September 2014

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