Special Issue "Nanoparticles in Immunology"
A special issue of Nanomaterials (ISSN 2079-4991).
Deadline for manuscript submissions: closed (31 August 2017)
A/Prof. Dr. Neil M. O'Brien-Simpson
Oral Health CRC, Melbourne Dental School, 720 Swanston Street, The University of Melbourne, Carlton Victoria 3010, Australia
Interests: particle delivery; targeted particle systems; chemical biology; antimicrobial peptides; vaccines; mucosal immunology; T cell immunity; innate immunity
Recent developments in nanotechnology have led to a wide range of nanomaterials, with the purpose of interacting with the immune system. These novel nanomaterials are designed as carriers for a drug or antigen cargo to stimulate or suppress the immune system, encompass targeting moieties, such as peptides or antibodies, to direct material to certain cells to enhance immunity or imaging of immune system compartments. Furthermore, the inherent properties of nanomaterials are being used, enhanced, or altered to effect routes of application, delivery, and release of cargo.
This Special Issue of Nanomaterials will capture the current knowledge in this area, through original research and reviews so as to provide critical dialogue in synthesis of nanomaterials for a specific immunological applications.
Prof. Dr. Neil M. O'Brien-Simpson
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- immune response
- antigen delivery
- mucosal immunity
- immune targeting
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Tentative title: The interplay between nanoparticles and neutrophils
Authors: Min-Hsien Lin, Chi-Feng Hung, Zih-Chan Lin, Jia-You Fang
Affiliations: Chang Gung University
Abstract: Inflammation is an immune response that indicates several pathophysiological conditions, including pathogen infection, tissue injury, and tumor growth, in human diseases. During the processes of infection, tumor growth and autoimmune responses, tissue-associated immune cells distributed in the body play a central role in the onset of inflammation and are actively involved in maintaining homeostasis. Nanoparticles for medical use are becoming an important material for application in diverse areas, including oncology, diagnosis and drug delivery. The research involved in nanomedicine is currently focused on the beneficial application for clinical practicability; however, the toxicity of nanoparticles is not usually taken into consideration. Most of the nanoparticles for diagnosis/therapy are administered via a parenteral route into the circulation. Neutrophils are the majority of blood cells in circulation. In response to foreign stimulation, the neutrophils can react first. Overexpressed activation of neutrophils can elicit tissue and organ damage, leading to pathogenesis and some diseases. This review describes the interactions between various nanoparticles and neutrophils. In this review, we principally focus on the effect of nanoparticles on the neutrophil-elicited inflammation and immunomodulation. The benefits of nanoparticles for neutrophil-related disorders are also discussed. The review ends by anticipating future developments and trends of nanoparticles for immune diseases.