Special Issue "Ribozymes and RNA Catalysis"
Deadline for manuscript submissions: closed (20 September 2016)
After the discovery of the first naturally occurring catalytic RNAs, more than 30 years ago, research in the field of ribozymes and RNA catalysis has made tremendous progress. In the 1990, most of the catalytic RNAs known today were identified in nature, and at the same time the powerful SELEX method (Systematic Evolution of Ligands by Exponential Enrichment) allowed the development of artificial ribozymes with rather diverse functionality. Over the years, investigation into the structure and mechanism of ribozymes led to a deep understanding of the catalytic strategies. Today, ribozymes are understood to an extent that allows rational design and engineering into catalytic RNAs with pre-defined function. However, there is still much to be learned. New ribozymes or novel genomic locations of known motifs in highly diverse genetic contexts in all branches of life are expected to be discovered by the help of high-throughput bioinformatics approaches. This Special Issue aims to provide a source of information on the ongoing discovery, characterization, engineering and application of ribozymes, and their biological functions.
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- conformational analysis
- co-transcriptional scission
- in vitro selection
- metal ions
- RNA cleavage
- RNA folding
- RNA ligation
- RNA processing
- RNA structure
- roling circle replication
- therapeutic RNA