Protein Biomarkers
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (30 June 2019) | Viewed by 284
Special Issue Editor
Interests: human Induced pluripotent stem cells (iPSCs); organoids; disease modeling; drug testing and discovery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the last few years, proteomic profiling technologies have had a tremendous impact on the diagnosis, management and follow-up of many human diseases. These approaches have provided new information that integrates the transcriptional profiling picture, adding, at the same time, a new level of complexity. Recently, the low molecular weight proteome obtained from plasma/serum has drawn the attention of the scientific community as a rapidly emerging frontier for protein biomarker discovery. At the same time, proteomic analysis may allow the detection of molecular changes correlated to drug response in preclinical models. These changes can be detected in the whole cell proteome, as well as in specific cell compartments or in functionally related groups of proteins. Relevant changes can also be detected in the secreted proteins, which might in some way be paralleled by changes detected in the serum proteome.
The present Special Issue aims to provide an update on protein biomarker discovery, with a special focus on the most recent and advanced proteomic technologies.
Prof. Dr. Giovanni Cuda
Guest Editor
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Keywords
- Protein Biomarkers
- Proteomics
- Mass Spectrometry
- 2D-Gel Electrophoresis
- Induced Pluripotent Stem Cells
- Human Disease Modelling
