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Special Issue "Drug Discovery from Microorganisms"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 28 February 2019

Special Issue Editors

Guest Editor
Prof. Jae Kyung Sohng

Department of Life Science and Biochemical Engineering, Sun Moon University, Chungnam, Republic of Korea
Website | E-Mail
Interests: Natural products; Actinomycetes; Streptomyces; Flavonoids; Antibiotics; Anticancer drugs; Metabolic engineering; Synthetic Biology; Enzymatic modifications
Guest Editor
Dr. Dipesh Dhakal

Department of Life Science and Biochemical Engineering, Sun Moon University, Chungnam, Republic of Korea
Website | E-Mail
Interests: Rare Actinomycetes; Secondary metabolites; Biosynthetic gene cluster; Biosynthetic mechanisms; Biological activities; Synthetic biology

Special Issue Information

Dear Colleagues,

Natural products (NPs) biosynthesized by microorganisms are prominent source of compounds with pharmacological values, thus established as the best starting point in the drug discovery process. Generally these compounds are biosynthesized in microorganisms through versatile metabolic pathways. They are often termed as “secondary metabolites” (SM) as they are synthesized like primary metabolites by producer organisms but may not be essential for their own metabolic processes. These SM or their derivatives are most frequently utilized as “drug leads” for the treatment of different disease conditions. Different biological approaches such as the utilization of synthetic biology tools, metabolic engineering techniques and precise enzymatic modifications have assisted in developing novel molecules with novel structural/functional diversities from the producer organism. This Special Issue aims to include research or review papers focused on key aspects of drug discovery from micro-organisms, including the isolation and characterization of novel structures, the study of biosynthetic mechansims, or the assessment of the biological activities of diverse microbe-derived molecules.

Prof. Jae Kyung Sohng
Dr. Dipesh Dhakal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Microbe-derived biomolecules
  • Isolation and characteriztion
  • Biosynthetic mechansims
  • Biological activities
  • Structural modifications

Published Papers

This special issue is now open for submission.
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