Special Issue "Metal Based Drugs: Opportunities and Challenges"
Deadline for manuscript submissions: closed (10 July 2017)
Prof. Dr. Patrick Gamez
Metal-based drugs are used for a wide range of human diseases, beyond their well-known applications in cancer (cisplatin) or rheumatoid arthritis (auranofin). For instance, a number of metal complexes have been developed for the treatment/cure of a variety of disorders such as ulcers, diabetes, inflammatory and cardiovascular diseases, and so on.
The development of drugs based on coordination compounds, i.e., metal complexes, offers the possibility of great structural versatility, compared to purely organic molecules, as they are generated from the combination of different metal ion(s) with distinct ligand(s). The binding of the ligand to the metal ion gives rise to drastic changes in the biological properties of both the organic (ligand) and the inorganic (metal) part. Metal complexes may exert their therapeutic effect through the interaction with cellular organelles, inhibition of enzymes, alteration of the cell membrane, enhanced lipophilicity, cell–cycle arrest, etc.
This Special Issue is aimed at providing a forum for the dissemination of information on the most recent and relevant research in this topical and exciting area of current investigation.
Prof. Dr. Patrick Gamez
Dr. Ana Belén Caballero
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- metal-based therapeutic agents
- contrast agents for Magnetic Resonance Imaging (MRI)
- chelation therapy
- antiparasitic agents