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Special Issue "Advances in Food Analysis"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 31 May 2019

Special Issue Editors

Guest Editor
Prof. Dr. Alessandra Gentili

Department of Chemistry, Sapienza University, Rome, Italy
Website | E-Mail
Interests: liquid chromatography; mass spectrometry; development of original extraction procedures (e.g. SPE prototypes; evaluation of last-generation materials as sorbents for SPE and liquid ionics/deep eutectic solvents for DLLME); development and validation of LC methods; LC-DAD-MS/MS profiling of organic micronutrients in foods and biological fluids
Guest Editor
Prof. Dr. Chiara Fanali

Departmental Faculty of Medicine and Surgery, Campus Bio-Medico University of Rome- Rome, Italy
Website | E-Mail
Interests: high-performance liquid chromatography; mass spectrometry; food bioactive compounds; method development and validation; liquid phase extraction; proteomics

Special Issue Information

Dear Colleagues,

Nowadays, the growing awareness of the close relation among diet, health and social development is stimulating demands for high levels of quality and safety in agro-food production, as well as new studies to fill gaps in the actual body of knowledge about food composition. For these reasons, modern research in food science and human nutrition is moving from classical methodologies to advanced instrumental platforms for comprehensive characterization. Non-destructive spectroscopic and imaging technologies are also proposed for food process monitoring and quality control in real-time.

This Special Issue is intended to highlight the most recent advancements and trends within the framework of food analysis. Research papers and reviews illustrating the most interesting developments related to sample preparation, separation science, spectroscopic techniques, sensors and biosensors, as well as investigations dealing with characterization of macronutrients, micronutrients and other biomolecules of interest are welcome.

We warmly invite our colleagues to submit their original contributions to this Special Issue in order to provide updates regarding alternative food sources (e.g., algae), functional foods, chiral or achiral bioactive compounds, effects of processing, contaminants, and every topic related to food science that is appealing to readers.

We would be delighted if you could respond to confirm your contribution and the proposed title by 30 November, 2018.

Prof. Dr. Alessandra Gentili
Prof. Dr. Chiara Fanali
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sample preparation
  • separation techniques
  • sensor analysis
  • spectroscopic techniques
  • food composition
  • food contaminants
  • natural products
  • characterization of alternative food sources
  • characterization of medicinal herbs

Published Papers (2 papers)

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Research

Open AccessArticle Selection and Identification of Novel Aptamers Specific for Clenbuterol Based on ssDNA Library Immobilized SELEX and Gold Nanoparticles Biosensor
Molecules 2018, 23(9), 2337; https://doi.org/10.3390/molecules23092337
Received: 21 August 2018 / Revised: 6 September 2018 / Accepted: 7 September 2018 / Published: 13 September 2018
PDF Full-text (3027 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
We describe a multiple combined strategy to discover novel aptamers specific for clenbuterol (CBL). An immobilized ssDNA library was used for the selection of specific aptamers using the systematic evolution of ligands by exponential enrichment (SELEX). Progress was monitored using real-time quantitative PCR
[...] Read more.
We describe a multiple combined strategy to discover novel aptamers specific for clenbuterol (CBL). An immobilized ssDNA library was used for the selection of specific aptamers using the systematic evolution of ligands by exponential enrichment (SELEX). Progress was monitored using real-time quantitative PCR (Q-PCR), and the enriched library was sequenced by high-throughput sequencing. Candidate aptamers were picked and preliminarily identified using a gold nanoparticles (AuNPs) biosensor. Bioactive aptamers were characterized for affinity, circular dichroism (CD), specificity and sensitivity. The Q-PCR amplification curve increased and the retention rate was about 1% at the eighth round. Use of the AuNPs biosensor and CD analyses determined that six aptamers had binding activity. Affinity analysis showed that aptamer 47 had the highest affinity (Kd = 42.17 ± 8.98 nM) with no cross reactivity to CBL analogs. Indirect competitive enzyme linked aptamer assay (IC-ELAA) based on a 5′-biotin aptamer 47 indicated the limit of detection (LOD) was 0.18 ± 0.02 ng/L (n = 3), and it was used to detect pork samples with a mean recovery of 83.33–97.03%. This is the first report of a universal strategy including library fixation, Q-PCR monitoring, high-throughput sequencing, and AuNPs biosensor identification to select aptamers specific for small molecules. Full article
(This article belongs to the Special Issue Advances in Food Analysis)
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Graphical abstract

Open AccessArticle Novel Electrochemical Sensors Based on Cuprous Oxide-Electrochemically Reduced Graphene Oxide Nanocomposites Modified Electrode toward Sensitive Detection of Sunset Yellow
Molecules 2018, 23(9), 2130; https://doi.org/10.3390/molecules23092130
Received: 30 July 2018 / Revised: 16 August 2018 / Accepted: 21 August 2018 / Published: 24 August 2018
PDF Full-text (3619 KB) | HTML Full-text | XML Full-text
Abstract
Control and detection of sunset yellow is an utmost demanding issue, due to the presence of potential risks for human health if excessively consumed or added. Herein, cuprous oxide-electrochemically reduced graphene nanocomposite modified glassy carbon electrode (Cu2O-ErGO/GCE) was developed for the
[...] Read more.
Control and detection of sunset yellow is an utmost demanding issue, due to the presence of potential risks for human health if excessively consumed or added. Herein, cuprous oxide-electrochemically reduced graphene nanocomposite modified glassy carbon electrode (Cu2O-ErGO/GCE) was developed for the determination of sunset yellow. The Cu2O-ErGO/GCE was fabricated by drop-casting Cu2O-GO dispersion on the GCE surface following a potentiostatic reduction of graphene oxide (GO). Scanning electron microscope and X-ray powder diffractometer was used to characterize the morphology and microstructure of the modification materials, such as Cu2O nanoparticles and Cu2O-ErGO nanocomposites. The electrochemical behavior of sunset yellow on the bare GCE, ErGO/GCE, and Cu2O-ErGO/GCE were investigated by cyclic voltammetry and second-derivative linear sweep voltammetry, respectively. The analytical parameters (including pH value, sweep rate, and accumulation parameters) were explored systematically. The results show that the anodic peak currents of Cu2O-ErGO /GCE are 25-fold higher than that of the bare GCE, due to the synergistic enhancement effect between Cu2O nanoparticles and ErGO sheets. Under the optimum detection conditions, the anodic peak currents are well linear to the concentrations of sunset yellow, ranging from 2.0 × 10−8 mol/L to 2.0 × 10−5 mol/L and from 2.0 × 10−5 mol/L to 1.0 × 10−4 mol/L with a low limit of detection (S/N = 3, 6.0 × 10−9 mol/L). Moreover, Cu2O-ErGO/GCE was successfully used for the determination of sunset yellow in beverages and food with good recovery. This proposed Cu2O-ErGO/GCE has an attractive prospect applications on the determination of sunset yellow in diverse real samples. Full article
(This article belongs to the Special Issue Advances in Food Analysis)
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