Special Issue "Diels-Alder Reaction"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 December 2012)
Prof. Dr. Raymond J. Giguere
Department of Chemistry, Skidmore College, 815 N. Broadway, Saratoga Springs, NY 12866, USA
Interests: intramolecular cycloadditions; microwave heating in organic synthesis; public perception of natural science
The Diels-Alder reaction, discovered in 1928, is widely recognized as one of the cornerstone synthetic organic reactions of the 20th century. In fact, it is one of the most commonly employed reactions for the synthesis of natural products, as well as for the rapid construction of cyclic and polycyclic compounds. The intramolecular extension of the Diels-Alder, first reported by Kurt Alder in 1952, led the way to a significant number of elegant synthetic achievements. Further historical developments (e.g., Lewis acid catalysis, frontier orbital theory, introduction of heteroatoms, comprehension of stereoelectronic features, solvent and temperature effects, the use of high pressure or microwave heating conditions, etc.) involving this Nobel-prize winning reaction have made the Diels-Alder reaction an efficient, reliable and powerful tool in the hands of synthetic chemists everywhere.
Molecules Special Issue on Diels-Alder chemistry will provide a timely venue for presenting key developments and important facets of this milestone reaction. I strongly encourage authors to submit papers for this Special Issue, and am hopeful that the topics published will assist in promoting novel applications of this exceptional process for the synthesis of organic molecules of interest and importance.
Prof. Raymond J. Giguere,
- Diels-Alder Reaction
- Hetero Diels-Alder
- [4 + 2]
Review: Diels-Alder Reactions of 12-Hydroxy-9(10®20)-5aH-abeo-abieta-1(10),8(9),12(13)-triene-11,14-dione
Molecules 2013, 18(6), 6969-6989; doi:10.3390/molecules18066969
Received: 1 March 2013; in revised form: 14 May 2013 / Accepted: 30 May 2013 / Published: 14 June 2013| Download PDF Full-text (497 KB)
Article: Growth of Fullerene Fragments Using the Diels-Alder Cycloaddition Reaction: First Step towards a C60 Synthesis by Dimerization
Molecules 2013, 18(2), 2243-2254; doi:10.3390/molecules18022243
Received: 25 December 2012; in revised form: 20 January 2013 / Accepted: 5 February 2013 / Published: 13 February 2013| Download PDF Full-text (576 KB)
Article: On the Catalytic Effect of Water in the Intramolecular Diels–Alder Reaction of Quinone Systems: A Theoretical Study
Molecules 2012, 17(11), 13687-13703; doi:10.3390/molecules171113687
Received: 18 September 2012; in revised form: 8 November 2012 / Accepted: 12 November 2012 / Published: 20 November 2012| Download PDF Full-text (454 KB) | Supplementary Files
Communication: On the Reaction of 1,3-Diphenylisobenzofuran and (2-Iodoethynyl)(phenyl)iodonium Triflate. A Unique Case of Oxygen Transfer from the Diels-Alder Adduct to the Diene
Molecules 2012, 17(8), 8795-8803; doi:10.3390/molecules17088795
Received: 13 June 2012; in revised form: 26 June 2012 / Accepted: 10 July 2012 / Published: 25 July 2012| Download PDF Full-text (380 KB) | Download XML Full-text | Supplementary Files
Last update: 4 March 2014