Special Issue "Compound Management"

Guest Editor
Mr. Paul Shinn
NIH Chemical Genomics Center, Rockville, MD, USA
E-Mail:
Interests: acoustic dispensing; liquid handling; automation; high throughput screening; automated compound storage; DMSO storage conditions; long term storage effects; efficient determination of compound quality/purity/solubilization/concentration; optimal compound collection size

No papers have been published in this special issue yet, see below for planned papers.

Dear Colleagues,

Compound management has become a multi-disciplinary field encompassing many facets of chemistry, engineering, software development, and database administration.  Multi-million dollar facilities have been constructed to warehouse and distribute compounds globally with the goal of quick turnaround.  In some cases best practices regarding storage of compounds in DMSO solution have been rationalized based on the need to meet the ever present demand of compound for HTS screening and follow-up.

Compound management, though, is no longer solely in the purview of big pharma.  The varieties of economical, commercially available screening libraries are widespread.  Liquid and plate handling instrumentation are more robust than ever, and the capital needed to procure them diminishes as newer technologies enter the market.  Compound management at this scale is allowing more researchers to explore novel chemical space in a more focused manner.

This special issue will focus on topics in compound management within the scope of Molecules.

Paul Shinn
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs).

• acoustic dispensing
• compound management of natural products
• orthogonal pooled screening strategies
• screening for synergistic effects
• DMSO storage conditions
• siRNA library management
• efficient determination of compound quality, purity, solubility and concentration