Special Issue "Click Chemistry"

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A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Synthesis".

Deadline for manuscript submissions: closed (31 July 2010)

Special Issue Editor

Guest Editor
Prof. Dr. Christian Girard
Unité de Technologies Chimiques & Biologiques pour la Santé, Equipe SEISAD - Synthèse Electrochimie, Imagerie et Systèmes Analytiques pour le Diagnostique, UMR 8258 CNRS / U 1022 INSERM, Ecole Nationale Supérieure de Chimie de Paris 11, rue P. & M. Curie, 75231 Paris cedex 05, France
Website: http://www.chimie-paristech.fr/fr/la_recherche/UTCBS/
E-Mail: christian-girard@enscp.fr
Phone: +33 1 44 27 67 48
Fax: +33-1 44 27 64 96

Special Issue Information

Dear Colleagues,

Click-chemistry is a new way of thinking molecular construction that emerges at the turn of this century. This concept, introduced by K. B. Sharpless, is based on the use of fast and efficient reactions between building blocks that opens the way to quasi-illimited variations in chemical architecture. Click-chemistry permits the construction of highly diversified structures through the use of reactive subunits, that can be joined using nucleophilic and electrophilic substitutions, ring opening reactions, cycloadditions reactions such as the copper (I)-modified Huisgen reaction and the Diels-Alder one, additions to unsaturated bonds, carbonyl chemistry, and so on. The scope of this new way of thinking molecular construction is large and has found many applications in classical organic synthesis, polymers and material sciences, as well as at the biological interface, with biocompatible conditions.

This Special Issue of Molecules has the objective to present articles that cover the use of click-chemistry to generate molecular diversity by organic synthesis (molecular libraries, chemical architecture, complexe structures, etc.), as well as its application at the frontier with other sciences.

Prof. Dr. Christian Girard
Guest Editor

Keywords

  • click-chemistry
  • organic synthesis
  • molecular diversity
  • methodology
  • application
  • interfaces with other sciences (pharmaceutical, biological, polymers, materials, etc.)

Published Papers (4 papers)

Molecules 2010, 15(8), 5768-5781; doi:10.3390/molecules15085768
Received: 30 June 2010; in revised form: 27 July 2010 / Accepted: 4 August 2010 / Published: 23 August 2010
Show/Hide Abstract | Cited by 7 | PDF Full-text (156 KB)

Molecules 2010, 15(5), 3087-3120; doi:10.3390/molecules15053087
Received: 29 March 2010; in revised form: 20 April 2010 / Accepted: 26 April 2010 / Published: 28 April 2010
Show/Hide Abstract | Cited by 8 | PDF Full-text (596 KB)

Molecules 2010, 15(3), 2039-2059; doi:10.3390/molecules15032039
Received: 8 February 2010; in revised form: 8 March 2010 / Accepted: 18 March 2010 / Published: 23 March 2010
Show/Hide Abstract | Cited by 28 | PDF Full-text (815 KB) | Supplementary Files

Molecules 2010, 15(1), 178-197; doi:10.3390/molecules15010178
Received: 1 December 2009; in revised form: 19 December 2009 / Accepted: 31 December 2009 / Published: 6 January 2010
Show/Hide Abstract | Cited by 14 | PDF Full-text (161 KB)

Last update: 27 February 2014

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