Special Issue "Click Chemistry"
Deadline for manuscript submissions: closed (31 July 2010)
Prof. Dr. Christian Girard
Laboratoire de Pharmacologie Chimique & Génétique (UMR 8151 CNRS / U 1022 INSERM), Synthèse Electrochimie, Imagerie et Systèmes Analytiques pour le Diagnostique (SEISAD), Ecole Nationale Supérieure de Chimie de Paris, rue Pierre et Marie Curie 11, 75231 Paris Cedex 05, France
Phone: +33 1 44 27 67 48
Fax: +33 1 43 25 79 75
Click-chemistry is a new way of thinking molecular construction that emerges at the turn of this century. This concept, introduced by K. B. Sharpless, is based on the use of fast and efficient reactions between building blocks that opens the way to quasi-illimited variations in chemical architecture. Click-chemistry permits the construction of highly diversified structures through the use of reactive subunits, that can be joined using nucleophilic and electrophilic substitutions, ring opening reactions, cycloadditions reactions such as the copper (I)-modified Huisgen reaction and the Diels-Alder one, additions to unsaturated bonds, carbonyl chemistry, and so on. The scope of this new way of thinking molecular construction is large and has found many applications in classical organic synthesis, polymers and material sciences, as well as at the biological interface, with biocompatible conditions.
This Special Issue of Molecules has the objective to present articles that cover the use of click-chemistry to generate molecular diversity by organic synthesis (molecular libraries, chemical architecture, complexe structures, etc.), as well as its application at the frontier with other sciences.
Prof. Dr. Christian Girard
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- organic synthesis
- molecular diversity
- interfaces with other sciences (pharmaceutical, biological, polymers, materials, etc.)
Molecules 2010, 15(1), 178-197; doi:10.3390/molecules15010178
Received: 1 December 2009; in revised form: 19 December 2009 / Accepted: 31 December 2009 / Published: 6 January 2010| Download PDF Full-text (161 KB)
Article: Cationic Heteroleptic Cyclometalated IridiumIII Complexes Containing Phenyl-Triazole and Triazole-Pyridine Clicked Ligands
Molecules 2010, 15(3), 2039-2059; doi:10.3390/molecules15032039
Received: 8 February 2010; in revised form: 8 March 2010 / Accepted: 18 March 2010 / Published: 23 March 2010| Download PDF Full-text (815 KB) |
Article: Automated Synthesis of a 96 Product-Sized Library of Triazole Derivatives Using a Solid Phase Supported Copper Catalyst
Molecules 2010, 15(5), 3087-3120; doi:10.3390/molecules15053087
Received: 29 March 2010; in revised form: 20 April 2010 / Accepted: 26 April 2010 / Published: 28 April 2010| Download PDF Full-text (596 KB)
Molecules 2010, 15(8), 5768-5781; doi:10.3390/molecules15085768
Received: 30 June 2010; in revised form: 27 July 2010 / Accepted: 4 August 2010 / Published: 23 August 2010| Download PDF Full-text (156 KB)
Last update: 24 August 2010