Special Issue "Chiroptical Techniques"

Guest Editor
Prof. Dr. Stig Allenmark
Department of Chemistry, Goteborg University, SE-41296 Goteborg, Sweden
Website: http://www2.chem.gu.se/staff/stig_allenmark.html
E-Mail:
Phone: +46 317723841
Fax: +46 317723840
Interests: enantioselectivity in chromatography and in catalytic reactions; chiroptical methods for solving stereochemical problems

Dear Colleagues,

As we all know, chirality plays a cruical role in the chemistry of living systems, since the macromolecules involved in the life processes are chiral. Therefore, proteins are often able to discriminate between enantiomers, which, among other things, has consequences for chiral compounds with pharmacological activity, where the enantiomers may show large differences in uptake, action, and metabolization. As a result, chiroptical techniques for studies and characterization of optically active compounds have become of great importance and today a multitude of methods based on the use of chiral light exist. Some of these can be coupled to enantioselective chromatographic separation techniques and used for detection, others can be used together with results from theoretical calculations of spectra for the determination of absolute configuration or -conformation. Of great interest here is the use of infrared radiation to study vibrational optical activity (VOA) and particularly the use of vibrational CD (VCD), since here the number of useful optically active transitions is larger than in electronic CD (ECD). Ab initio calculations of VCD spectra are also easier to perform. Thus, the variety of chiroptical techniques available or under development today has catalyzed stereochemical research and the instrumentation is continuously improved.

This Special Issue on Chiroptical Techniques is intended to attract researchers dealing with optically active compounds who want to contribute their latest results to the forum of Molecules. It is my hope that a good deal of interesting papers will be submitted that will reflect the potential and rapid development of the use of chiroptical techniques for studies in the chemical and associated fields.

Dr. Stig Allenmark
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs).

optical activity; circular birefringence; polarimetry; electric and magnetic transition moments; optical rotation; optical rotatory dispersion (ORD); Cotton effect; anisotropic refraction; anisotropic absorption; circular dichroism (CD) spectroscopy; rotational strength; circularly polarised light (cpl); dissymmetry factor; fluorescence detected CD (FDCD); anisotropic emission; circular polarization of emission (CPE); circularly polarized luminescence (CPL); sector rules; octant rule; absolute conformation; absolute configuration; induced CD; solid-state CD; coupled HPLC-CD; exciton coupling; exciton chirality; bisignate CD curves; couplets; time-resolved CD (TRCD); CD of anisotropic phases; vibrational optical activity (VOA); Raman optical activity (ROA); vibrational circular dichroism (VCD); theoretical calculation of CD-spectra