Special Issue "Advances in Medicinal Chemistry of Antibiotics"

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A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (31 August 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Françoise Van Bambeke
Pharmacologie cellulaire et moléculaire, Louvain Drug Research Institute, Université catholique de Louvain, Avenue Mounier 73 B1.73.05, 1200 Brussels, Belgium
E-Mail: francoise.vanbambeke@uclouvain.be
Phone: +32 2 764 73 78
Fax: +32 2 764 73 73
Interests: new antibiotics; pharmacokinetics and pharmacodynamics; intracellular infection; efflux transporters

Special Issue Information

Dear Colleagues,

In a world of increasing resistance, we have to urgently come with new, potent, weapons. Discovery of novel antibiotic classes acting on still unexploited targets remains a challenge. Another approach that has been followed quite intensively and successfully over the last years consists in refining our knowledge of structure-activity relationships to come with molecules showing an increased intrinsic activity, a reduced susceptibility to resistance mechanisms, an improved safety profile, or a better pharmacokinetic profile.
This special issue is aimed at presenting up-to-date reviews or promising experimental data on structure-activity relationships, either for existing classes of antibiotics or for new classes of antibiotics (meaning for which there is still no drug on the market).

Prof. Dr. Françoise Van Bambeke
Guest Editor

Keywords

  • structure-activity relationships
  • antibiotics
  • new antibacterial targets
  • activity towards multiresistant bacteria

Published Papers (4 papers)

by , , ,  and
Molecules 2012, 17(11), 12478-12505; doi:10.3390/molecules171112478
Received: 13 September 2012; in revised form: 5 October 2012 / Accepted: 17 October 2012 / Published: 24 October 2012
Show/Hide Abstract | Cited by 9 | PDF Full-text (456 KB) | HTML Full-text | XML Full-text

by , , , , ,  and
Molecules 2012, 17(10), 12243-12251; doi:10.3390/molecules171012243
Received: 13 September 2012; in revised form: 27 September 2012 / Accepted: 15 October 2012 / Published: 18 October 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (192 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , ,  and
Molecules 2012, 17(10), 12276-12286; doi:10.3390/molecules171012276
Received: 12 September 2012; in revised form: 8 October 2012 / Accepted: 17 October 2012 / Published: 18 October 2012
Show/Hide Abstract | Cited by 22 | PDF Full-text (179 KB) | HTML Full-text | XML Full-text

by , , ,  and
Molecules 2012, 17(8), 9129-9141; doi:10.3390/molecules17089129
Received: 17 July 2012; in revised form: 25 July 2012 / Accepted: 26 July 2012 / Published: 2 August 2012
Show/Hide Abstract | Cited by 5 | PDF Full-text (273 KB) | HTML Full-text | XML Full-text
abstract graphic

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.


Last update: 4 March 2014

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