Special Issue "Cell-Penetrating Peptides (CPPs)"
Deadline for manuscript submissions: 31 January 2019
Dr. Rakesh K. Tiwari
Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, 9401 Jeronimo Road, Irvine, California 92618-1908, United States
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Interests: peptide chemsitry; cell-penetrating peptides; peptide- and peptidomimetics-based therapeutics; neurotherapeutics; antimicrobial peptides; anticancer drug conjugates; peptide-based drug delivery systems and nanomedicines
Cell-penetrating peptides (CPPs) containing 5–30 amino acid residues efficiently pass across cell membranes and are commonly used to deliver a wide range of cargoes intracellularly. CPPs consist of amino acids with a cationic and amphipathic nature. There are several examples of well-established CPPs, such as polyarginine, penetratin, TAT, SynB1, SynB3, PTD-4, MAP, and SBP. These CPPs can deliver drugs or macromolecules to the cytoplasm or the nucleus of cells. The growing interest in the area of peptide–drug conjugates utilizing CPPs to deliver cell impermeable molecules reflects their emerging applications. These CPPs are also utilized to understand transporters' properties, membrane dynamics, and mechanisms of internalization of micro/macromolecules.
This Special Issue aims to provide an update on the recent developments in the areas of design, optimization, and employment of CPPS for specific applications, such as drug delivery systems and diagnostic tools, and to explore the mechanisms of CPPs cellular internalization and their combination with nanoparticles.
Dr. Rakesh K. Tiwari
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Design and Development of CPPs
- Membrane dynamic or biophysical studies
- Mechanistic understanding of CPPs
- CPPs with nanoparticle in diagnostic and therapy
- Macromolecule delivery with CPPs
- CPPs for brain delivery
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Article type: review
Author: Jean-Luc Poyet and Justine Habault