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Special Issue "Bioactive Nucleosides and Nucleotides"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 31 May 2018

Special Issue Editor

Guest Editor
Prof. Dr. Christian Ducho

Department of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2 3, 66 123 Saarbrücken, Germany
Website | E-Mail
Interests: medicinal chemistry; antibiotics; natural products; nucleosides; oligonucleotides

Special Issue Information

Dear Colleagues,

It is my pleasure to announce this Special Issue of Molecules on "Bioactive Nucleosides and Nucleotides". Analogues of nucleosides and nucleotides have had a tremendous impact, not only as (bio)chemical tools, but particularly also as drugs for human therapy. Nucleoside and nucleotide derivatives are currently widely used to treat cancer and viral infections, with the introduction of the highly potent anti-HCV drug Sofosbuvir (a nucleotide prodrug) representing the most recent milestone. However, nucleosides also find increasing interest as antibacterial drug candidates, which are urgently needed in the context of emerging resistances against established antibiotics.

For this Special Issue, we welcome contributions from all fields of nucleoside and nucleotide chemistry, may they be related to fundamental science or potential pharmaceutical applications. This also includes work that is mainly or even exclusively focused on organic synthesis. The synthetic preparation of nucleoside and nucleotide analogues is not trivial, and I strongly feel that there is an unfortunate tendency to overlook this highly important part of our daily work as chemists.

Prof. Dr. Christian Ducho
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • nucleosides and nucleotides
  • organic synthesis
  • anti-cancer agents
  • antiviral agents
  • antibacterial agents
  • chemical tools and probes

Published Papers

This special issue is now open for submission.
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