Special Issue "Lipidomics"
A special issue of Metabolites (ISSN 2218-1989).
Deadline for manuscript submissions: closed (25 December 2011)
Prof. Dr. Dietrich A. Volmer
Institute for Bioanalytical Chemistry, Department of Chemistry, Saarland University, 66123 Saarbrücken, Germany
Interests: metabolomics; lipidomics; proteomics; analytical method development; structure elucidation; quantitative mass spectrometry; ionization mechanisms and gas-phase ion chemistry
Lipids play essential roles in biological systems and many diseases involve changes in lipid metabolism and perturbed lipid pathways. Even though lipid analysis is widely applied in the biological sciences, lipidomics, the detailed and comprehensive analysis of lipids in a cell or tissue, is just at the beginning of its evolution. The chemical complexity of lipids, the difficulties of studying lipids in their biological framework, and the requirement to relate identity and modulation of bioactive lipids with function of genes and proteins require sophisticated high resolution analytical tools for their structural and quantitative analysis. Importantly, lipidomics techniques are increasingly used in studies of biological function, and for diagnostic and prognostic purposes (biomarkers). A considerable amount of research effort goes into data crunching and data mining of lipidomics datasets, which is a key to successful comprehensive exploration of lipidomics data as a function of treatment, genotype or phenotype.
Therefore, this special issue of Metabolites will be dedicated to publishing current advances on bioanalytical techniques, discovery and characterization of novel lipid biomarkers, functional lipidomics, clinical applications of lipidomics, and biocomputational approaches to data-mining and databases of lipidomics datasets.
Prof. Dr. Dietrich Volmer
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- lipid metabolism
- lipid profiling
- lipid fingerprints
- global profiling of lipids
- metabolic phenotype
- lipid biomarkers
- mass spectrometry
- untargeted lipidomics
- targeted lipidomics
- data mining
- clinical lipidomics
Review: Accurate Quantification of Lipid Species by Electrospray Ionization Mass Spectrometry — Meets a Key Challenge in Lipidomics
Metabolites 2011, 1(1), 21-40; doi:10.3390/metabo1010021
Received: 8 October 2011; in revised form: 2 November 2011 / Accepted: 4 November 2011 / Published: 11 November 2011| Download PDF Full-text (223 KB) | Download XML Full-text
Metabolites 2012, 2(1), 1-18; doi:10.3390/metabo2010001
Received: 28 November 2011; in revised form: 21 December 2011 / Accepted: 22 December 2011 / Published: 4 January 2012| Download PDF Full-text (509 KB) | Download XML Full-text
Metabolites 2012, 2(1), 19-38; doi:10.3390/metabo2010019
Received: 23 November 2011; in revised form: 22 December 2011 / Accepted: 24 December 2011 / Published: 5 January 2012| Download PDF Full-text (411 KB) | Download XML Full-text
Article: Quantification of Signaling Lipids by Nano-Electrospray Ionization Tandem Mass Spectrometry (Nano-ESI MS/MS)
Metabolites 2012, 2(1), 57-76; doi:10.3390/metabo2010057
Received: 29 November 2011; in revised form: 4 January 2012 / Accepted: 6 January 2012 / Published: 16 January 2012| Download PDF Full-text (947 KB) | Download XML Full-text | Supplementary Files
Review: Lipidomics of Glycosphingolipids
Metabolites 2012, 2(1), 134-164; doi:10.3390/metabo2010134
Received: 28 November 2011; in revised form: 27 January 2012 / Accepted: 30 January 2012 / Published: 2 February 2012| Download PDF Full-text (484 KB) | Download XML Full-text
Article: Shotgun Lipidomics by Sequential Precursor Ion Fragmentation on a Hybrid Quadrupole Time-of-Flight Mass Spectrometer
Metabolites 2012, 2(1), 195-213; doi:10.3390/metabo2010195
Received: 24 December 2011; in revised form: 10 February 2012 / Accepted: 13 February 2012 / Published: 20 February 2012| Download PDF Full-text (3041 KB) | Download XML Full-text | Supplementary Files
Metabolites 2012, 2(1), 254-267; doi:10.3390/metabo2010254
Received: 19 January 2012; in revised form: 23 February 2012 / Accepted: 24 February 2012 / Published: 2 March 2012| Download PDF Full-text (528 KB) | Download XML Full-text | Supplementary Files
Article: Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet
Metabolites 2012, 2(2), 366-381; doi:10.3390/metabo2020366
Received: 5 April 2012; in revised form: 21 May 2012 / Accepted: 4 June 2012 / Published: 18 June 2012| Download PDF Full-text (441 KB) | Download XML Full-text
Last update: 12 October 2012