Special Issue "Analytical Techniques in Metabolomics"

Quicklinks

A special issue of Metabolites (ISSN 2218-1989).

Deadline for manuscript submissions: closed (30 April 2012)

Special Issue Editor

Guest Editor
Dr. Per Bruheim
Department of Biotechnology, Norwegian University of Science and Technology, 7034 Trondheim, Norway
Website: http://www.ntnu.edu/employees/per.bruheim
E-Mail: per.bruheim@biotech.ntnu.no
Interests: mass spectrometry; metabolomics; metabolic engineering; secondary metabolites; biomakers

Special Issue Information

Dear Colleagues,

Metabolomics face particular analytical challenges due to the diverse physico-chemical properties of the metabolites; ranging from highly negatively charged organic acids and phosphometabolites to hydrophobic species such as fatty acids, steroids and pigments. Hence, at present no single analytical method can cover the whole Metabolome. Mass spectrometry (MS) and magnetic resonance (NMR) are the two main analytical technologies for analysis of metabolite pools, the former in combination with separation techniques as gas and liquid chromatography. Broadly, Metabolomics can be divided in two approaches: targeted and non-targeted analysis; the former delivering quantification of known metabolites while the latter approach is mostly used to classify samples and potential identification of unknown metabolites. Both approaches have benefitted strongly by recent technological developments, as the analytical instruments have become more sensitive and with higher resolution and accuracy.  Therefore, this special issue in Metabolites will cover both qualitative and quantitative analytical techniques used to analyze metabolite pools as well as aspects on sample preparation and data processing.

Dr. Per Bruheim
Guest Editor

Published Papers (5 papers)

by ,  and
Metabolites 2013, 3(3), 787-819; doi:10.3390/metabo3030787
Received: 10 July 2013; in revised form: 30 August 2013 / Accepted: 2 September 2013 / Published: 11 September 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (1870 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , , ,  and
Metabolites 2012, 2(4), 775-795; doi:10.3390/metabo2040775
Received: 2 August 2012; in revised form: 2 October 2012 / Accepted: 10 October 2012 / Published: 18 October 2012
Show/Hide Abstract | Cited by 3 | PDF Full-text (420 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , , , , , ,  and
Metabolites 2012, 2(3), 496-515; doi:10.3390/metabo2030496
Received: 8 June 2012; in revised form: 31 July 2012 / Accepted: 6 August 2012 / Published: 16 August 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (300 KB) | HTML Full-text | XML Full-text

by ,  and
Metabolites 2012, 2(3), 398-428; doi:10.3390/metabo2030398
Received: 2 May 2012; in revised form: 29 June 2012 / Accepted: 4 July 2012 / Published: 6 July 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (769 KB) | HTML Full-text | XML Full-text

by  and
Metabolites 2012, 2(2), 337-365; doi:10.3390/metabo2020337
Received: 1 March 2012; in revised form: 2 April 2012 / Accepted: 9 April 2012 / Published: 20 April 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (943 KB) | HTML Full-text | XML Full-text

Last update: 27 February 2014

Metabolites EISSN 2218-1989 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert