E-Mail Alert

Add your e-mail address to receive forthcoming issues of this journal:

Journal Browser

Journal Browser

Special Issue "Graphene in Biomedical Application"

A special issue of Materials (ISSN 1996-1944).

Deadline for manuscript submissions: 30 December 2018

Special Issue Editor

Guest Editor
Prof. Minna Hakkarainen

Department of Fibre and Polymer Technology, KTH Royal Institute of Technology, Teknikringen 58, 11428 Stockholm, Sweden
Website | E-Mail
Interests: biobased materials; degradable polymers; recycling; graphene oxide; carbon dots; polymer nanocomposites; materials for packaging; biomedical applications and water purification

Special Issue Information

Dear Colleagues

It is my pleasure to invite you to submit reviews, regular research papers and communications to this Special Issue on “Graphene in Biomedical Applications”. This issue provides a forum to present recent results and developments, highlighting the progress and vast future possibilities of graphene and graphene derivatives in biomedical applications. The physical and chemical properties of graphene derivatives vary over wide span depending on, e.g., dimensions, surface functionality, covalent derivatization or functionalization by electrostatic and hydrophobic interactions. Thanks to the palette of structures and properties the potential applications of graphene derivatives in the field of biomedicine are many ranging from imaging and biosensors to photodynamic therapy, drug/gene delivery and tissue engineering, where graphene can provide multiple new functionalities and options. Of great interest is also the antibacterial activity and good biocompatibility in cell cultures demonstrated by many of the graphene derivatives, such as graphene oxide and reduced graphene oxide.

I look forward to your submissions within this fascinating topic.

Prof. Minna Hakkarainen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Graphene
  • Biomedical
  • Drug delivery
  • Gene Delivery
  • Tissue Engineering
  • Imaging
  • Biosensors
  • Biocompatibility
  • Antimicrobial
  • Bioactivity

Published Papers (2 papers)

View options order results:
result details:
Displaying articles 1-2
Export citation of selected articles as:

Research

Open AccessArticle Fabrication and Characterization of an Electrospun PHA/Graphene Silver Nanocomposite Scaffold for Antibacterial Applications
Materials 2018, 11(9), 1673; https://doi.org/10.3390/ma11091673
Received: 14 August 2018 / Revised: 21 August 2018 / Accepted: 23 August 2018 / Published: 10 September 2018
PDF Full-text (2603 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Many wounds are unresponsive to currently available treatment techniques and therefore there is an immense need to explore suitable materials, including biomaterials, which could be considered as the crucial factor to accelerate the healing cascade. In this study, we fabricated polyhydroxyalkanoate-based antibacterial mats
[...] Read more.
Many wounds are unresponsive to currently available treatment techniques and therefore there is an immense need to explore suitable materials, including biomaterials, which could be considered as the crucial factor to accelerate the healing cascade. In this study, we fabricated polyhydroxyalkanoate-based antibacterial mats via an electrospinning technique. One-pot green synthesized graphene-decorated silver nanoparticles (GAg) were incorporated into the fibres of poly-3 hydroxybutarate-co-12 mol.% hydroxyhexanoate (P3HB-co-12 mol.% HHx), a co-polymer of the polyhydroxyalkanoate (PHA) family which is highly biocompatible, biodegradable, and flexible in nature. The synthesized PHA/GAg biomaterial has been characterized by field emission scanning electron microscopy (FESEM), elemental mapping, thermogravimetric analysis (TGA), UV-visible spectroscopy (UV-vis), and Fourier transform infrared spectroscopy (FTIR). An in vitro antibacterial analysis was performed to investigate the efficacy of PHA/GAg against gram-positive Staphylococcus aureus (S. aureus) strain 12,600 ATCC and gram-negative Escherichia coli (E. coli) strain 8739 ATCC. The results indicated that the PHA/GAg demonstrated significant reduction of S. aureus and E. coli as compared to bare PHA or PHA- reduced graphene oxide (rGO) in 2 h of time. The p value (p < 0.05) was obtained by using a two-sample t-test distribution. Full article
(This article belongs to the Special Issue Graphene in Biomedical Application)
Figures

Graphical abstract

Open AccessFeature PaperArticle Nano-Graphene Oxide Functionalized Bioactive Poly(lactic acid) and Poly(ε-caprolactone) Nanofibrous Scaffolds
Materials 2018, 11(4), 566; https://doi.org/10.3390/ma11040566
Received: 27 January 2018 / Revised: 22 March 2018 / Accepted: 5 April 2018 / Published: 6 April 2018
Cited by 2 | PDF Full-text (33295 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A versatile and convenient way to produce bioactive poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) electrospun nanofibrous scaffolds is described. PLA and PCL are extensively used as biocompatible scaffold materials for tissue engineering. Here, biobased nano graphene oxide dots (nGO) are incorporated in PLA
[...] Read more.
A versatile and convenient way to produce bioactive poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) electrospun nanofibrous scaffolds is described. PLA and PCL are extensively used as biocompatible scaffold materials for tissue engineering. Here, biobased nano graphene oxide dots (nGO) are incorporated in PLA or PCL electrospun scaffolds during the electrospinning process aiming to enhance the mechanical properties and endorse osteo-bioactivity. nGO was found to tightly attach to the fibers through secondary interactions. It also improved the electrospinnability and fiber quality. The prepared nanofibrous scaffolds exhibited enhanced mechanical properties, increased hydrophilicity, good cytocompatibility and osteo-bioactivity. Therefore, immense potential for bone tissue engineering applications is anticipated. Full article
(This article belongs to the Special Issue Graphene in Biomedical Application)
Figures

Graphical abstract

Back to Top